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HomeProduct name listTRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE

TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE

  • CAS NO.:58656-04-5
  • Empirical Formula: C18H34BF4P
  • Molecular Weight: 368.24
  • MDL number: MFCD03840580
  • EINECS: 672-607-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-31 13:32:20
TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE Structural

What is TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE?

Chemical properties

White powder

The Uses of TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE

Tricyclohexylphosphonium Tetrafluoroborate acts as a reagent in the synthesis of potent JAK2 inhibitor BMS-911543 as a potential treatment for myeloproliferative disorders, preparation of Lapatinib intermediate via arylation of furfural with bromochlorofluorobenzyloxyphenylquinazolinamine, structure-activity relationships of carboline and carbazole derivatives as ATP-competitive kinesin spindle protein inhibitors.

The Uses of TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE

suzuki reaction

The Uses of TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE

Tricyclohexylphosphine tetrafluoroborate may be used in the following processes:

  • As a ligand for preparing C-homoaporphine alkaloids via microwave-assisted direct-arylation.
  • To synthesize poly-[9,9-bis(3-propylamide-2-methylpropyl sulfonic acid) fluorene]-co-(4,4′-diphenyl) (PFDBSO3H), which can be employed as a template and doping agent for enhancing the conductivity of poly(3,4-ethylenedioxythiophene) (PEDOT) films.
  • To improve the reactivity of palladium-catalyzed Suzuki-Miyaura cross-coupling reaction between MIDA boronates and less activated alkenyl tosylates.

General Description

Tricyclohexylphosphine tetrafluoroborate (PCy3·HBF4) is an inexpensive and air-stable phosphine ligand, commonly used in cross-coupling reactions.

Properties of TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE

Melting point: 164 °C(lit.)
storage temp.  Keep in dark place,Sealed in dry,Room Temperature
solubility  Dichloromethane (Slightly), Methanol (Slightly)
form  Powder
color  White
Water Solubility  Soluble in water.

Safety information for TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE

Signal word Danger
Pictogram(s)
ghs
Corrosion
Corrosives
GHS05
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H314:Skin corrosion/irritation
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P260:Do not breathe dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.
P501:Dispose of contents/container to..…

Computed Descriptors for TRICYCLOHEXYLPHOSPHONIUM TETRAFLUOROBORATE

InChIKey KZGFMSRKDNYVKL-UHFFFAOYSA-N

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