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HomeProduct name listToloxatone

Toloxatone

Synonym(s):5-(Hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone;Humoryl

  • CAS NO.:29218-27-7
  • Empirical Formula: C11H13NO3
  • Molecular Weight: 207.23
  • MDL number: MFCD00865391
  • EINECS: 249-522-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-09 19:38:33
Toloxatone Structural

What is Toloxatone?

Description

Toloxatone is a selective, reversible and competitive inhibitor of type A monoamine oxidase (MAO-A) which shows clinical utility as an antidepressant. It is reportedly free of the "cheese effect" in man, possibly due to the reversible nature of its inhibitory effect on intestinal MAO-A in the presence of high concentrations of tyramine.

Originator

Delalande (France)

The Uses of Toloxatone

Toloxatone is a monoamine oxidase-A (MAO-A) inhibitor.

Definition

ChEBI: 5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one is a member of the class of oxazolidinones that is 5-(hydroxymethyl)-1,3-oxazolidin-2-one substituted by a 3-methylphenyl group at position 3. It is a member of toluenes, an oxazolidinone and a primary alcohol.

brand name

HUMORYL

Properties of Toloxatone

Melting point: 76°
Boiling point: 358.9±21.0 °C(Predicted)
Density  1.245±0.06 g/cm3(Predicted)
storage temp.  Inert atmosphere,2-8°C
solubility  DMSO: >10mg/mL
form  solid
pka 14.05±0.10(Predicted)
color  White to off-white

Safety information for Toloxatone

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Toloxatone

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