Toloxatone
Synonym(s):5-(Hydroxymethyl)-3-(3-methylphenyl)-2-oxazolidinone;Humoryl
- CAS NO.:29218-27-7
- Empirical Formula: C11H13NO3
- Molecular Weight: 207.23
- MDL number: MFCD00865391
- EINECS: 249-522-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-09 19:38:33
What is Toloxatone?
Description
Toloxatone is a selective, reversible and competitive inhibitor of type A monoamine oxidase (MAO-A) which shows clinical utility as an antidepressant. It is reportedly free of the "cheese effect" in man, possibly due to the reversible nature of its inhibitory effect on intestinal MAO-A in the presence of high concentrations of tyramine.
Originator
Delalande (France)
The Uses of Toloxatone
Toloxatone is a monoamine oxidase-A (MAO-A) inhibitor.
Definition
ChEBI: 5-(hydroxymethyl)-3-(3-methylphenyl)-1,3-oxazolidin-2-one is a member of the class of oxazolidinones that is 5-(hydroxymethyl)-1,3-oxazolidin-2-one substituted by a 3-methylphenyl group at position 3. It is a member of toluenes, an oxazolidinone and a primary alcohol.
brand name
HUMORYL
Properties of Toloxatone
Melting point: | 76° |
Boiling point: | 358.9±21.0 °C(Predicted) |
Density | 1.245±0.06 g/cm3(Predicted) |
storage temp. | Inert atmosphere,2-8°C |
solubility | DMSO: >10mg/mL |
form | solid |
pka | 14.05±0.10(Predicted) |
color | White to off-white |
Safety information for Toloxatone
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Toloxatone
New Products
ALUMINIUM IODIDE 100 GM BUFFER CAPSULE PH 7.0 - 10 CAP BUFFER SOLUTION PH 9.5 (BORATE) EZEE BLUE GEL STAINER BORAX CARMINE (GRENACHERS ALCOHOLIC) POTASSIUM IODATE - IODIDE SOLN 0.1 N Dabigatran Acyl-O3-D-Glucuronide Trifluoroacetic Acid Salt Isofolic Acid Dabigatran 2-O-acylglucuronide metabolite Dabigatran Acyl-?-D- glucuronide Trifluroacetic Acid Erythromycin EP Impurity A Desloratidine Related Compound ARelated products of tetrahydrofuran
Duloxetine
3-PHENYL-2-OXAZOLIDINONE
2-Oxazolidinone, 5-hydroxymethyl-3-(m-tolyl)-, carbamate
HYDROXYPROPYLCARBAMATE
Toloxatone
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