Titanium dioxide
Synonym(s):Titanium dioxide;Titanium;Titanium(IV) oxide;Titania;TiOxide
- CAS NO.:13463-67-7
- Empirical Formula: O2Ti
- Molecular Weight: 79.8658
- MDL number: MFCD00011269
- EINECS: 236-675-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-05-14 16:18:08
What is Titanium dioxide?
Absorption
When male and female rats were fed a diet containing titanium dioxide (100 g/kg) for a period of about 32 days, a significant retention of titanium of 0.06 and 0.11 mg/kg wet weight was found only in the muscles; no retention was observed in the liver, spleen, kidney, bone, plasma, or erythrocytes
Toxicity
Rat - LD50 Intratracheal (>100ug/kg ) Effects: Structural or functional changes in bronchi and trachea. There is inadequate evidence in humans for the carcinogenicity of titanium dioxide. Cancer in experimental animals: There is sufficient evidence in experimental animals for the carcinogenicity of titanium dioxide. Overall evaluation: Titanium dioxide is possibly carcinogenic to humans (Group 2B).
Description
Titanium dioxide is derived in its purest form from rutile beach sand. Used as paint pigment for its brilliant whiteness since the early 20th century, titanium dioxide is noted for its ability to withstand color change and its high refractive index. Today, it is widely used in sunblock not only as a pigment, but also for its ability to protect skin against UV light.
Description
Titanium dioxide, TiO2, is a white powder and has the greatest hiding power of all white pigments. It is noncombustible; however, it is a powder and, when suspended in air, may cause a dust explosion if an ignition source is present. It is not listed in the DOT Hazardous Materials Table, and the DOT does not consider it hazardous in transportation. The primary uses are as a white pigment in paints, paper, rubber, and plastics; in cosmetics; in welding rods; and in radioactive decontamination of the skin.
The Uses of Titanium dioxide
Titanium dioxide is an extreme white and bright compound with high index of refraction. In paints it is a white pigment and an opacifying agent.It is in house paints, water paints, lacquers, enamels, paper filling and coating, rubber, plastics, printing ink, synthetic fabrics, floor coverings, and shoe whiteners. Also, it is used in colorants for ceramics and coatings for welding rods. A rutile form of the dioxide is used in synthetic gem stones.
Background
Titanium dioxide, also known as titanium(IV) oxide or titania, is the naturally occurring oxide of titanium. It is used as a pigment under the names titanium white, Pigment White 6 (PW6), or CI 77891. It is typically extracted from ilmenite, rutile and anatase.
Indications
Titanium dioxide is used in most sunscreens to block UVA and UVB rays, similar to zinc oxide.
What are the applications of Application
Titanium(IV) oxide is a bacteriocide commonly used in paint and cosmetics
Metabolism
Rats were intraperitoneal injected with 1.60 g/100 g body wt of TiO(2) in saline solution. Organs (liver, spleen, lung) were processed for histological evaluation. Reactive oxygen species (ROS) in alveolar macrophages obtained by bronchoalveolar lavage (BAL) were evaluated using the nitroblue tetrazolium test and quantitative evaluation by digital image analysis. The histological analysis of organs revealed the presence of titanium in the parenchyma of these organs with no associated tissue damage. Although in lung alveolar macrophages TiO(2) induced a significant rise in ROS generation, it failed to cause tissue alteration. This finding may be attributed to an adaptive response.
Properties of Titanium dioxide
Melting point: | 1840 °C |
Boiling point: | 2900 °C |
Density | 4.26 g/mL at 25 °C(lit.) |
Flash point: | 2500-3000°C |
storage temp. | Store at +5°C to +30°C. |
solubility | Practically insoluble in water. It does not dissolve in dilute mineral acids but dissolves slowly in hot concentrated sulfuric acid. |
form | powder |
color | White to slightly yellow |
Water Solubility | insoluble |
Safety information for Titanium dioxide
Signal word | Danger |
Pictogram(s) |
Corrosion Corrosives GHS05 Health Hazard GHS08 |
GHS Hazard Statements |
H318:Serious eye damage/eye irritation H373:Specific target organ toxicity, repeated exposure |
Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P314:Get medical advice/attention if you feel unwell. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P501:Dispose of contents/container to..… |
Computed Descriptors for Titanium dioxide
Abamectin manufacturer
Nyne Organics Pvt Ltd
UNILOSA INTERNATINAL PRIVATE LIMITED
Choice Chemicals
JSK Chemicals
Neelikon Food Dyes Chemicals Ltd
Parshwanath Group of Indusries
LANXESS India Pvt. Ltd.
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