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HomeProduct name listTiotropium bromide hydrate

Tiotropium bromide hydrate

  • CAS NO.:139404-48-1
  • Empirical Formula: C19H22BrNO4S2.H2O
  • Molecular Weight: 490.43
  • MDL number: MFCD00867027
  • EINECS: 690-508-4
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-03-11 14:26:33
Tiotropium bromide hydrate Structural

What is Tiotropium bromide hydrate?

Chemical properties

White or yellowish-white powder or crystals.

The Uses of Tiotropium bromide hydrate

Tiotropium Bromide hydrate is a hydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist. Although tiotropium Bromide (Spiriva; Tiova; BA 679BR; tiopropium) doe

What are the applications of Application

Tiotropium Bromide Monohydrate is a biochemical for proteomics research

Definition

ChEBI: Tiotropium bromide hydrate is a hydrate that is the monohydrate form of tiotropium bromide. Used for maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease. It has a role as a muscarinic antagonist and a bronchodilator agent.

Clinical Use

Maintenance treatment of chronic obstructive pulmonary disease

Drug interactions

Potentially hazardous interactions with other drugs
Avoid administration with other anti-cholinergic drugs.
Anti-arrhythmics: increased risk of antimuscarinic side effects with disopyramide.

Metabolism

Tiotropium is excreted largely unchanged in the urine, although it may undergo some metabolism by non-enzymatic cleavage and by the cytochrome P450 isoenzymes CYP2D6 and CYP3A4.

Properties of Tiotropium bromide hydrate

storage temp.  Store at -20°C
solubility  Sparingly soluble in water, soluble in methanol, practically insoluble in methylene chloride.
form  Powder
CAS DataBase Reference 139404-48-1(CAS DataBase Reference)

Safety information for Tiotropium bromide hydrate

Computed Descriptors for Tiotropium bromide hydrate

InChIKey MQLXPRBEAHBZTK-SEINRUQRSA-M

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