Tiotropium bromide hydrate
- CAS NO.：139404-48-1
- Empirical Formula: C19H22BrNO4S2.H2O
- Molecular Weight: 490.43
- MDL number: MFCD00867027
- EINECS: 690-508-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 20:33:22
What is Tiotropium bromide hydrate?
Chemical properties
White or yellowish-white powder or crystals.
The Uses of Tiotropium bromide hydrate
Tiotropium Bromide hydrate is a hydrate of tiotropium bromide (Spiriva; Tiova; BA 679BR; tiopropium) that is an anticholinergic and bronchodilator and a muscarinic receptor antagonist. Although tiotropium Bromide (Spiriva; Tiova; BA 679BR; tiopropium) doe
What are the applications of Application
Tiotropium Bromide Monohydrate is a biochemical for proteomics research
Definition
ChEBI: Tiotropium bromide hydrate is a hydrate that is the monohydrate form of tiotropium bromide. Used for maintenance treatment of airflow obstruction in patients with chronic obstructive pulmonary disease. It has a role as a muscarinic antagonist and a bronchodilator agent.
Clinical Use
Maintenance treatment of chronic obstructive pulmonary disease
Drug interactions
Potentially hazardous interactions with other drugs
Avoid administration with other anti-cholinergic
drugs.
Anti-arrhythmics: increased risk of antimuscarinic
side effects with disopyramide.
Metabolism
Tiotropium is excreted largely unchanged in the urine, although it may undergo some metabolism by non-enzymatic cleavage and by the cytochrome P450 isoenzymes CYP2D6 and CYP3A4.
Properties of Tiotropium bromide hydrate
| storage temp. | Store at -20°C |
| solubility | Sparingly soluble in water, soluble in methanol, practically insoluble in methylene chloride. |
| form | Powder |
| CAS DataBase Reference | 139404-48-1(CAS DataBase Reference) |
Safety information for Tiotropium bromide hydrate
Computed Descriptors for Tiotropium bromide hydrate
| InChIKey | MQLXPRBEAHBZTK-SEINRUQRSA-M |
Tiotropium bromide hydrate manufacturer
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