Tinoridine
- CAS NO.：24237-54-5
- Empirical Formula: C17H20N2O2S
- Molecular Weight: 316.42
- MDL number: MFCD00401417
- EINECS: 246-102-0
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-15 10:44:00
What is Tinoridine?
Originator
Nonflamin,Yoshitomi,Japan,1971
The Uses of Tinoridine
Ethyl 2-Amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (Tinoridine) targets pantothenate synthetase which plays a significant role in the biosynthesis of pantothenate in Mycobacterium tuberculosis (MTB).
Definition
ChEBI: Tinoridine is a thienopyridine.
Manufacturing Process
A solution of 1-benzyl-4-piperidone, ethyl cyanoacetate, powdery sulfur and morpholine in ethanol is heated moderately under reflux for about 20 minutes to dissolve the powdery sulfur. The mixture is heated under reflux for one further hour to complete the reaction. On standing at room temperature, the mixture yields a precipitate. The precipitate is collected by filtration, washed well with methanol and recrystallized from methanol to give 2-amino-6- benzyl-3-ethoxycarbonyl-4,5,6,7-tetrahydrothieno(2,3-c)-pyridine as almost colorless needles melting at 112° to 113°C.
brand name
Tinoridine Hydrochloride is JAN.
Therapeutic Function
Antiinflammatory
Properties of Tinoridine
| Melting point: | 112-113°C |
| Boiling point: | 493.5±45.0 °C(Predicted) |
| Density | 1.256±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | Chloroform (Slightly) |
| form | Solid |
| pka | 6.29±0.20(Predicted) |
| color | Light Yellow |
Safety information for Tinoridine
Computed Descriptors for Tinoridine
New Products
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