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HomeProduct name listTinoridine

Tinoridine

  • CAS NO.:24237-54-5
  • Empirical Formula: C17H20N2O2S
  • Molecular Weight: 316.42
  • MDL number: MFCD00401417
  • EINECS: 246-102-0
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 23:02:33
Tinoridine Structural

What is Tinoridine?

Originator

Nonflamin,Yoshitomi,Japan,1971

The Uses of Tinoridine

Ethyl 2-Amino-6-benzyl-4,5,6,7-tetrahydrothieno[2,3-c]pyridine-3-carboxylate (Tinoridine) targets pantothenate synthetase which plays a significant role in the biosynthesis of pantothenate in Mycobacterium tuberculosis (MTB).

Definition

ChEBI: Tinoridine is a thienopyridine.

Manufacturing Process

A solution of 1-benzyl-4-piperidone, ethyl cyanoacetate, powdery sulfur and morpholine in ethanol is heated moderately under reflux for about 20 minutes to dissolve the powdery sulfur. The mixture is heated under reflux for one further hour to complete the reaction. On standing at room temperature, the mixture yields a precipitate. The precipitate is collected by filtration, washed well with methanol and recrystallized from methanol to give 2-amino-6- benzyl-3-ethoxycarbonyl-4,5,6,7-tetrahydrothieno(2,3-c)-pyridine as almost colorless needles melting at 112° to 113°C.

brand name

Tinoridine Hydrochloride is JAN.

Therapeutic Function

Antiinflammatory

Properties of Tinoridine

Melting point: 112-113°C
Boiling point: 493.5±45.0 °C(Predicted)
Density  1.256±0.06 g/cm3(Predicted)
storage temp.  2-8°C
solubility  Chloroform (Slightly)
form  Solid
pka 6.29±0.20(Predicted)
color  Light Yellow

Safety information for Tinoridine

Computed Descriptors for Tinoridine

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