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HomeProduct name listTilorone dihydrochloride

Tilorone dihydrochloride

Synonym(s):2,7-Bis[2-(diethylamino)ethoxy]-9-fluorenone dihydrochloride

Tilorone dihydrochloride Structural

What is Tilorone dihydrochloride?

Description

Tilorone is an orally active, antiviral compound that induces interferon production and is reported to have antitumor, anti-inflammatory, and neuroprotective actions. With chronic administration, tilorone induces lysosomal glycosaminoglycan storage, rendering glycosaminoglycans resistant to enzymatic degradation.

Chemical properties

Orange-yellow crystalline powder

The Uses of Tilorone dihydrochloride

Tilorone dihydrochloride is an orally active, interferon-inducing antiviral agent.

The Uses of Tilorone dihydrochloride

Tilorone dihydrochloride was used to study the interaction of drugs with synthetic self-complementary DNA by SPR (Surface Plasmon Resonance).

What are the applications of Application

Tilorone dihydrochloride is A carbonyl compound is an antiviral for proteomics research

Definition

ChEBI: Tilorone dihydrochloride is the dihydrochloride salt of tilorone. It is used as an antiviral drug to treat influenza, herpes infection, viral hepatitis, acute respiratory viral infections and SARS. It has a role as an anti-inflammatory agent, an antineoplastic agent, an interferon inducer, a nicotinic acetylcholine receptor agonist and an antiviral drug. It contains a tilorone(2+).

brand name

Tilorone is INN.

General Description

Effect of tilorone dihydrochloride on the changes of transmembrane potential of mitochondrial membranes of the isolated rat hepatocytes has been investigated. Tilorone dihydrochloride is an orally active, interferon-inducing antiviral agent.

Properties of Tilorone dihydrochloride

Melting point: 230-233 °C(lit.)
storage temp.  Sealed in dry,Room Temperature
solubility  Methanol (Slightly)
form  Solid
color  Orange
Merck  14,9440
CAS DataBase Reference 27591-69-1(CAS DataBase Reference)

Safety information for Tilorone dihydrochloride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
ghs
Health Hazard
GHS08
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
H351:Carcinogenicity
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P308+P313:IF exposed or concerned: Get medical advice/attention.

Computed Descriptors for Tilorone dihydrochloride

InChIKey BSVYJQAWONIOOU-UHFFFAOYSA-N

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