Tilmicosin
Synonym(s):20-Deoxo-20-(3,5-dimethyl-1-piperidinyl)desmycosin
- CAS NO.：108050-54-0
- Empirical Formula: C46H80N2O13
- Molecular Weight: 869.15
- MDL number: MFCD00864842
- EINECS: 639-676-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-12-18 14:15:30
What is Tilmicosin?
Chemical properties
White Solid
The Uses of Tilmicosin
A Macrolide antibiotic.
The Uses of Tilmicosin
Tilmicosin is a semi-synthetic antibiotic derived from desmycosin (tylosin B), a minor co-metabolite of tylosin. Tilmicosin is produced by reductive amination of desmycosin. Desmycosin itself is prepared by the partial hydrolysis of tylosin with the loss of the mycarosyl sugar. The piperidinyl group at C20 of tilmicosin provides a wider spectrum of antibiotic action, in particular good protection against Pasteurella in livestock.
The Uses of Tilmicosin
Macrolide antibiotic structurally related to tylosin. Antibacterial
What are the applications of Application
Tilmicosin is a Macrolide antibiotic
Veterinary Drugs and Treatments
Tilmicosin is indicated for the treatment of bovine or ovine respiratory diseases (BRD) caused by Mannheimia (Pasturella) haemolytica.
Properties of Tilmicosin
| Melting point: | >97°C (dec.) |
| Boiling point: | 926.6±65.0 °C(Predicted) |
| alpha | D23 +12.75° (c = 0.010004 in CHCl3, 5 cm) |
| Density | 1.18±0.1 g/cm3(Predicted) |
| storage temp. | Inert atmosphere,Store in freezer, under -20°C |
| solubility | Acetone (Slightly), DMSO (Slightly), Methanol (Sparingly) |
| form | neat |
| form | Solid |
| pka | pKa (66% DMF): 7.4, 8.5(at 25℃) |
| color | White to Off-White |
| EPA Substance Registry System | Tilmicosin (108050-54-0) |
Safety information for Tilmicosin
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Tilmicosin
| InChIKey | JTSDBFGMPLKDCD-XVFHVFLVSA-N |
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