Tiazofurine
- CAS NO.：60084-10-8
- Empirical Formula: C9H12N2O5S
- Molecular Weight: 260.269
- MDL number: MFCD00866494
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is Tiazofurine?
Chemical properties
White Solid
The Uses of Tiazofurine
Tiazofurin has antitumor activity and is a potential therapeutic agent in the treatment of cancer. Tiazofurin acts as an inhibitor of Inosine-5'-monophosphate (IMP) dehydrogenase.
The Uses of Tiazofurine
Tiazofurin has antitumor activity and is a potential therapeutic agent in the treatment of cancer. Tiazofurin acts as an inhibitor of Inosine-5''-monophosphate (IMP) dehydrogenase.
Definition
ChEBI: A C-glycosyl compound that is 1,3-thiazole-4-carboxamide in which the hydrogen at position 2 has been replaced by a beta-D-ribofuranosyl group. It is metabolised to thiazole-4-carboxamide adenine dinucle tide (TAD), a selective inhibitor of inosine monophosphate dehydrogenase (IMP dehydrogenase).
brand name
Tiazofurine is INN.
Properties of Tiazofurine
| Melting point: | 145-146° |
| alpha | D25 -9° (c = 0.5 in ethanol) |
| Density | 1.4797 (rough estimate) |
| refractive index | 1.6800 (estimate) |
| storage temp. | under inert gas (nitrogen or Argon) at 2–8 °C |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated), Water (Slightly) |
| form | Solid |
| color | White to Pale Beige |
| Stability: | Very Very Hygroscopic |
Safety information for Tiazofurine
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Tiazofurine
New Products
Tert-butyl bis(2-chloroethyl)carbamate 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL N-octanoyl benzotriazole 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid DIETHYL AMINOMALONATE HYDROCHLORIDE 1,1’-CARBONYLDIIMIDAZOLE R-2-BENZYLOXY PROPIONIC ACID 1,1’-CARBONYLDI (1,2-4 TRIAZOLE) N-METHYL INDAZOLE-3-CARBOXYLIC ACID (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 5-BROMO-2CYANO PYRIDINE 5,6-Dimethoxyindanone 5-broMo-2-chloro-N-cyclopentylpyriMidin-4-aMine 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
![TIAZOFURINE, [3H]-](https://img.chemicalbook.in/StructureFile/ChemBookStructure4/GIF/CB5685826.gif)
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