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HomeProduct name listTHIONAZIN

THIONAZIN

Synonym(s):O,O-Diethyl O-(2-pyrazinyl) phosphorothioate

  • CAS NO.:297-97-2
  • Empirical Formula: C8H13N2O3PS
  • Molecular Weight: 248.24
  • MDL number: MFCD00055349
  • EINECS: 206-049-6
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-05-15 10:43:39
THIONAZIN Structural

What is THIONAZIN?

Chemical properties

Amber liquid. Slightly soluble in water; miscible with most organic solvents.

The Uses of THIONAZIN

Nematocide; insecticide.

Definition

ChEBI: Thionazin is an organic thiophosphate.

General Description

Amber liquid. Pure compound is almost colorless; technical product is light brown to tan. Used in insecticides, fungicides, and nematocides. Not registered as a pesticide in the U.S.

Reactivity Profile

Organothiophosphates, such as THIONAZIN, are susceptible to formation of highly toxic and flammable phosphine gas in the presence of strong reducing agents such as hydrides. Partial oxidation by oxidizing agents may result in the release of toxic phosphorus oxides.

Hazard

Toxic by ingestion, inhalation, and skin absorption; cholinesterase inhibitor.

Health Hazard

Cholinesterase inhibitor. (Non-Specific -- Organic Phosphate Compound, Liquid, Poison B). Poisonous; may be fatal if inhaled, swallowed or absorbed through skin. Contact may cause burns to skin and eyes.

Health Hazard

Extremely toxic by ingestion and skinabsorption; cholinesterase inhibitor; exhibitsacute, delayed, and chronic effect; symptomsof cholinergic effects include excessive salivation, lacrimation, blurred vision, musclespasms, headache, weakness, mental confusion, vomiting, diarrhea, stomach pain, convulsions, and coma; also causes shortnessof breath, respiratory depression, and respiratory paralysis; ingestion of small quantity(0.5–1.59) could be fatal to adult humans;poisoning effects may onset several hoursafter exposure.
LD50 oral (rat): 3.5–6 mg/kg
LD50 oral (mouse): 5 mg/kg
LD50 skin (rat): 8 mg/kg
LD50 skin (guinea pig): 10 mg/kg.

Fire Hazard

(Non-Specific -- Organic Phosphate Compound, Liquid, Poison B). THIONAZIN may burn but does not ignite readily. (Non-Specific -- Organic Phosphate Compound, Liquid, Poison B). Fire may produce irritating or poisonous gases.

Safety Profile

Poison by ingestion, skin contact, and ocular routes. A cholinesterase inhibitor type of insecticide. When heated to decomposition it emits highly toxic fumes of NOx, POx, and SOx. See also PARATHION.

Properties of THIONAZIN

Melting point: -1.7℃
Boiling point: bp 80°
Density  1.204-1.210 g/cm3 (25 ºC)
refractive index  1.5131 (589.3 nm 25℃)
Flash point: 100 °C
storage temp.  2-8°C
solubility  Chloroform (Sparingly), Ethyl Acetate (Slightly), Methanol (Slightly)
pka -1.22±0.10(Predicted)
form  liquid
Water Solubility  1.14g/L(25 ºC)
BRN  884916
Stability: Hygroscopic
EPA Substance Registry System Thionazin (297-97-2)

Safety information for THIONAZIN

Signal word Danger
Pictogram(s)
ghs
Skull and Crossbones
Acute Toxicity
GHS06
Precautionary Statement Codes P262:Do not get in eyes, on skin, or on clothing.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P270:Do not eat, drink or smoke when using this product.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.

Computed Descriptors for THIONAZIN

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