Thalidomide-NH-C6-NH2 TFA
- CAS NO.：2093386-51-5
- Empirical Formula: C21H25F3N4O6
- Molecular Weight: 486.45
- MDL number: MFCD32690101
- Update Date: 2024-07-02 08:55:17
What is Thalidomide-NH-C6-NH2 TFA?
Biological Activity
Thalidomide-NH-C6-NH2 TFA is a synthesized E3 ligase ligand-linker conjugate that incorporates the Thalidomide based cereblon ligand and a linker used in PROTAC technology[1].
References
[1]. Wang Z, et al. Proteolysis Targeting Chimeras for the Selective Degradation of Mcl-1/Bcl-2 Derived from Nonselective Target Binding Ligands. J Med Chem. 2019 Sep 12;62(17):8152-8163.
Properties of Thalidomide-NH-C6-NH2 TFA
| solubility | Soluble in DMSO |
| form | Solid |
| color | Light yellow to yellow |
Safety information for Thalidomide-NH-C6-NH2 TFA
Computed Descriptors for Thalidomide-NH-C6-NH2 TFA
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