Tetramethylammonium chloride
Synonym(s):Tetramethylammonium chloride;TMA
- CAS NO.：75-57-0
- Empirical Formula: C4H12ClN
- Molecular Weight: 109.6
- MDL number: MFCD00011628
- EINECS: 200-880-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-21 22:41:43
What is Tetramethylammonium chloride?
Chemical properties
white crystals
The Uses of Tetramethylammonium chloride
Chemical intermediate, catalyst, inhibitor.
The Uses of Tetramethylammonium chloride
Tetramethylammonium chloride along with N-hydroxyphthalimide and xanthone may be used as an efficient chloride catalytic system for the aerobic oxidation of hydrocarbons to form the corresponding oxygenated compounds. It may also be used as a phase transfer catalyst for the synthesis of aryl fluorides via selective chloride/fluoride exchange reaction of activated aryl chlorides with potassium fluoride in solid-liquid phase.
The Uses of Tetramethylammonium chloride
TMAC may be used in ion-exchange procedures to show the increase of pH in understanding the chemical behaviour of catalyst [CTA]Si-MCM-41 using Knoevenagel condensation model.
Definition
ChEBI: N,N,N-Trimethylmethanaminium chloride is an organic molecular entity.
General Description
Tetramethylammonium chloride is a quaternary ammonium salt commonly used as a catalyst due to its thermal stability and also tolerance towards strong aqueous bases or nucleophiles.
Safety Profile
Poison by ingestion, intraperitoneal, and subcutaneous routes. When heated to decomposition it emits very toxic fumes of NOx, NH3, and Cl-. See also CHLORIDES.
Purification Methods
Crystallise the chloride from EtOH, EtOH/CHCl3, EtOH/diethyl ether, acetone/EtOH (1:1), isopropanol or water. Traces of the free amine can be removed by washing with CHCl3. [Beilstein 4 IV 145.]
Properties of Tetramethylammonium chloride
| Melting point: | >300 °C (lit.) |
| Boiling point: | 165.26°C (rough estimate) |
| Density | 1,17 g/cm3 |
| refractive index | 1.5320 (estimate) |
| storage temp. | Store below +30°C. |
| solubility | methanol: 0.1 g/mL, clear, colorless |
| form | Hygroscopic Crystalline Powder |
| color | White to ivory |
| Specific Gravity | 1.169 |
| PH Range | 6 - 8 |
| PH | 6-8 (100g/l, H2O, 20℃) |
| Odor | Odorless |
| Water Solubility | >60 g/100 mL (20 ºC) |
| Sensitive | Hygroscopic |
| λmax | λ: 260 nm Amax: 0.02 λ: 280 nm Amax: 0.02 |
| BRN | 2496575 |
| Stability: | Stable. Incompatible with strong oxidizing agents, water. Hygroscopic. |
| CAS DataBase Reference | 75-57-0(CAS DataBase Reference) |
| NIST Chemistry Reference | Tetramethylammonium chloride(75-57-0) |
| EPA Substance Registry System | Tetramethylammonium chloride (75-57-0) |
Safety information for Tetramethylammonium chloride
| Signal word | Danger |
| Pictogram(s) |
 Skull and Crossbones Acute Toxicity GHS06  Health Hazard GHS08  Environment GHS09 |
| GHS Hazard Statements |
H300:Acute toxicity,oral H311:Acute toxicity,dermal H315:Skin corrosion/irritation H370:Specific target organ toxicity, single exposure H411:Hazardous to the aquatic environment, long-term hazard |
| Precautionary Statement Codes |
P260:Do not breathe dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician. |
Computed Descriptors for Tetramethylammonium chloride
Abamectin manufacturer
ACME SUJAN CHEMICALS
Dishman Carbogen Amcis Ltd (Dishman Group)
Kenoor Organics Private Limited
Yogi Enterprise
Tritech Catalyst and Intermediate Pvt Ltd
Tatva Chintan Pharma Chem Limited
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