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HomeProduct name listTetrahydrobiopterin

Tetrahydrobiopterin

Synonym(s):(6R)-BH4

Tetrahydrobiopterin Structural

What is Tetrahydrobiopterin?

The Uses of Tetrahydrobiopterin

Tetrahydrobiopterin is a naturally occurring essential cofactor of the three aromatic amino acid hydroxylase enzymes, used in the degradation of amino acid phenylalanine and in the biosynthesis of the neurotransmitters serotonin, melatonin, dopamine, norepinephrine , epinephrine, and is a cofactor for the production of nitric oxide by the nitric oxide synthases. Chemically, its structure is that of a reduced pteridine derivative.

Definition

ChEBI: 5,6,7,8-tetrahydrobiopterin is a tetrahydropterin, a member of biopterins and a diol. It has a role as a prosthetic group, a coenzyme, a nutraceutical and a human metabolite.

Properties of Tetrahydrobiopterin

Melting point: >202°C (dec.)
Boiling point: 506.6±60.0 °C(Predicted)
Density  1.89±0.1 g/cm3(Predicted)
storage temp.  -20°C
solubility  Aqueous Acid (Slightly), DMSO (Slightly), Water (Slightly)
form  Solid
pka 14.22±0.20(Predicted)
color  White to Off-White
Stability: Hygroscopic

Safety information for Tetrahydrobiopterin

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Tetrahydrobiopterin

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