Tetrafluoro-1-propanol
- CAS NO.:76-37-9
- Empirical Formula: C3H4F4O
- Molecular Weight: 132.06
- MDL number: MFCD00004676
- EINECS: 200-955-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-24 19:19:26
What is Tetrafluoro-1-propanol?
Chemical properties
colourless liquid
The Uses of Tetrafluoro-1-propanol
2,2,3,3-Tetrafluoro-1-propanol, is used as an essential fluorinated fine chemical, the main application of TFP is as a dye solvent in CD-R(W) and DVD-R(W) industry. It is also used in making textile treatment agent and pharmaceuticals. This chemical is an ideal replacement for Freon 22 detergent.
General Description
2,2,3,3-Tetrafluoro-1-propanol (TFP) is extensively used as the solvent. Mineralization and defluoridation of TFP by UV oxidation in a novel three-phase fluidized bed reactor was reported. Desorption of activated carbon loaded with TFP by supercritical carbon dioxide in a rotating packed bed was investigated.
Purification Methods
Tetrafluoro-1-propanol (450mL) is added to a solution of 2.25g of NaHSO3 in 90mL of water, shaken vigorously and set aside for 24hours. The fraction distilling at or above 99o is refluxed for 4hours with 5-6g of KOH and rapidly distilled, followed by a final fractional distillation. [Kosower & Wu J Am Chem Soc 83 3142 1961.] Alternatively, shake the alcohol with alumina for 24hours, dry it overnight with anhydrous K2CO3 and distil it, taking the middle fraction (b 107-108o). [Beilstein 1 IV 2438.]
Properties of Tetrafluoro-1-propanol
Melting point: | -15°C |
Boiling point: | 109 °C |
Density | 1.48 g/mL at 20 °C(lit.) |
refractive index | n |
Flash point: | 110 °F |
storage temp. | Sealed in dry,2-8°C |
form | Liquid |
pka | 13.05±0.10(Predicted) |
Specific Gravity | 1.481.471 |
color | Clear colorless |
Water Solubility | Soluble in water. |
Merck | 14,9206 |
BRN | 1738264 |
Stability: | Stable. Flammable. Incompatible with strong oxidizing agents, strong bases, sodium, potassium, acid chlorides, acid anhydrides. |
CAS DataBase Reference | 76-37-9(CAS DataBase Reference) |
NIST Chemistry Reference | 2,2,3,3-Tetrafluoro-1-propanol(76-37-9) |
EPA Substance Registry System | 1-Propanol, 2,2,3,3-tetrafluoro- (76-37-9) |
Safety information for Tetrafluoro-1-propanol
Signal word | Danger |
Pictogram(s) |
Flame Flammables GHS02 Skull and Crossbones Acute Toxicity GHS06 |
GHS Hazard Statements |
H226:Flammable liquids H319:Serious eye damage/eye irritation H331:Acute toxicity,inhalation |
Precautionary Statement Codes |
P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Tetrafluoro-1-propanol
Abamectin manufacturer
VGS SYNTHESIS PRIVATE LIMITED
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