Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name listtert-Butylamine

tert-Butylamine

Synonym(s):2-Amino-2-methylpropane;TBA;tert-Butylamine

  • CAS NO.:75-64-9
  • Empirical Formula: C4H11N
  • Molecular Weight: 73.14
  • MDL number: MFCD00008050
  • EINECS: 200-888-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:15:32
tert-Butylamine Structural

What is tert-Butylamine?

Chemical properties

tert-Butylamine is a colorless liquid with a typical amine-like odor. It is one of the four isomeric amines of butane, the others being n-butylamine, sec-butylamine and isobutylamine. Butylamines are highly flammable, colorless liquids (n-turns yellow on standing) with ammoniacal or fishlike odors. tert-Butylamine is used in the preparation of insecticides, pharmaceuticals, oil additives, and rubber accelerators.

The Uses of tert-Butylamine

tert-butylamine is used as a precursor for the preparation of rubber accelerators, pharmaceuticals and dyes. It is employed in synthesis of N-tert-butyl-acetamide, isoquinolines, pyridines, decumbenine, sulfontes, sulfonamides and methyl beta-ketophosphonate. It is also used in the study the effect of amines in influencing atmospheric sulfuric acid - water nucleation, hydroamination of terminal alkynes and measuring the surface acidity of solid catalyst. It acts as an indicator molecule in the study of NMR -based pH determination method.

Definition

ChEBI: Tert-butylamine is a primary aliphatic amine that is ethylamine substituted by two methyl groups at position 1. It is a conjugate base of a tert-butylammonium.

Production Methods

tert-Butylamine is manufactured by reacting isobutylamine with sulfuric acid followed by cyanide to tert-butylformamide. Hydrolysis yields t-butylamine. It is used as a solvent and in organic syntheses.

Preparation

tert-Butylamine is produced commercially by direct amination of isobutylene using zeolite catalysts:
NH3 + CH2=C(CH3)2 → H2NC(CH3)3
The Ritter reaction of isobutene with hydrogen cyanide is not useful because it produces too much waste.
(CH3)2C=CH2 + HCN + H2O → (CH3)3CNHCHO
(CH3)3CNHCHO + H2O → (CH3)3CNH2 + HCO2H
In the laboratory, it can be prepared by the hydrogenolysis of 2,2-dimethylethylenimine, or via tert-butylphthalimide.

What are the applications of Application

Tert-Butylamine is also used for the production of herbicides, i.e., terbacil and the triazines terbutylazine, terbumeton, and terbutryn and insecticides (e.g., diafenthiuron). A derivative has also been proposed as stabilizer for cosmetics.

General Description

Tert-butylamine appears as a clear colorless liquid with an ammonia-like odor. Flash point 70°F. Less dense (at 6.2 lb / gal) than water. Vapors heavier than air. Toxic oxides of nitrogen produced during combustion.

Air & Water Reactions

Highly flammable. May be sensitive to air . Soluble in water.

Reactivity Profile

tert-Butylamine neutralizes acids in exothermic reactions to form salts plus water. May be incompatible with isocyanates, halogenated organics, peroxides, phenols (acidic), epoxides, anhydrides, and acid halides. Flammable gaseous hydrogen is generated in combination with strong reducing agents, such as hydrides. Undergoes highly exothermic reaction with 2,2-dibromo-1,3-dimethylcyclopropanoic acid [J. Chem. Soc., 1, 1979, 2324].

Hazard

Skin irritant. Flammable, dangerous fire risk.

Health Hazard

Inhalation causes irritation of nose, mouth, and lungs. Ingestion causes irritation of mouth and stomach. Contact with liquid causes severe irritation of eyes and moderate irritation of skin.

Fire Hazard

Special Hazards of Combustion Products: Toxic oxides of nitrogen may form in fire.

Safety Profile

Poison by ingestion. Moderately toxic to humans by inhalation. A corrosive liquid. See also n-BUTYLAMINE and AMINES. Very dangerous fire hazard when exposed to heat or flame. Very exothermic reaction with 2,2-dibromo-l,3 dimethylcyclopropanoic acid. To fight fire, use alcohol foam. When heated to decomposition it emits toxic fumes of NOx.

Potential Exposure

Alert: (n-isomer): Possible risk of forming tumors, suspected of causing genetic defects, suspected reprotoxic hazard, Primary irritant (w/o allergic reaction), (sec-isomer): Drug. n-Butylamine is used in pharmaceuticals; dyestuffs, rubber, chemicals, emulsifying agents; photography, desizing agents for textiles; pesticides, and synthetic agents. sec-Butylamine is used as a fungistate. tert-Butylamine is used as a chemical intermediate in the production of tert-Butylaminoethyl methacrylate (a lube oil additive); as an intermediate in the production of rubber and in rust preventatives and emulsion deterrents in petroleum products. It is used in the manufacture of several drugs

Shipping

UN1125 n-Butylamine, Hazard Class: 3; Labels: 3—Flammable liquid, 8—Corrosive material. UN2014 Isobutylamine, Hazard Class: 3; Labels: 3—Flammable liquid, 8—Corrosive material

Purification Methods

Dry it with KOH or LiAlH4, and/or distil it from CaH2 or BaO. [Beilstein 4 IV 657.]

Incompatibilities

May form explosive mixture with air. May accumulate static electrical charges, and may causeignition of its vapors. n-Butylamine is a weak base; reacts with strong oxidizers and acids, causing fire and explosion hazard. Incompatible with organic anhydrides; isocyanates, vinyl acetate; acrylates, substituted allyls; alkylene oxides; epichlorohydrin, ketones, aldehydes, alcohols, glycols, phenols, cresols, caprolactum solution. Attacks some metals in presence of moisture. The tert-isomer will attack some forms of plastics

Waste Disposal

Use a licensed professional waste disposal service to dispose of this material. Dissolve or mix the material with a combustible solvent and burn in a chemical incinerator equipped with an afterburner andscrubber. All federal, state, and local environmental regulations must be observed.

Properties of tert-Butylamine

Melting point: -67 °C (lit.)
Boiling point: 46 °C (lit.)
Density  0.696 g/mL at 25 °C (lit.)
vapor density  2.5 (vs air)
vapor pressure  5.7 psi ( 20 °C)
refractive index  n20/D 1.377(lit.)
Flash point: −36.4 °F
storage temp.  Store below +30°C.
solubility  water: miscible1000g/L at 25°C
form  Liquid
pka 10.68(at 25℃)
color  Clear
Odor Like ammonia.
PH 12 (100g/l, H2O, 20℃)
explosive limit 1.5-9.2%(V)
Odor Threshold 0.17ppm
Water Solubility  MISCIBLE
Sensitive  Air Sensitive
Merck  14,1545
BRN  605267
Dielectric constant 4.3099999999999996
Stability: Stable. Incompatible with strong acids, strong oxidizing agents. Highly flammable.
CAS DataBase Reference 75-64-9(CAS DataBase Reference)
NIST Chemistry Reference 2-Propanamine, 2-methyl-(75-64-9)
EPA Substance Registry System tert-Butylamine (75-64-9)

Safety information for tert-Butylamine

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Corrosion
Corrosives
GHS05
ghs
Skull and Crossbones
Acute Toxicity
GHS06
GHS Hazard Statements H225:Flammable liquids
H302:Acute toxicity,oral
H314:Skin corrosion/irritation
H331:Acute toxicity,inhalation
H412:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P273:Avoid release to the environment.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for tert-Butylamine

tert-Butylamine manufacturer

Vinati Organics Limited

1Y
Phone:+91-8308091236
Whatsapp: +91- 8308091236
product: tert -Butylamine 98%
Inquiry

BASF India Limited

1Y
Phone:+91-2262785600
product: tert -Butylamine 98%
Inquiry

Krishna Solvechem Ltd.

1Y
Phone:+91-2261230213
Whatsapp: +91 8657457331
product: tert -Butylamine 75-64-9 / 94896-77-2 98%
Inquiry

S D Fine Chem Limited

1Y
Phone:+91-9323715856
Whatsapp: +91-9323715856
product: 75-64-9 / 94896-77-2 tert -Butylamine 99%
Inquiry

AKASH PHARMA EXPORTS

1Y
Phone:+91-9846039283
Whatsapp: +91- 9846039283
product: Tert Butyl Amine 99%
Inquiry

ARRAKIS INDUSTRIES LLP

1Y
Phone:+91-7499586750
Whatsapp: +91- 7499586750
product: 75-64-9 99%
Inquiry

SS Reagents and Chemicals

1Y
Phone:+91-7981238883
Whatsapp: +91-7981238883
product: Tert-Butylamine 75-64-9 99%
Inquiry

Anand Agencies

Maharashtra
Phone:91-9075014125
Whatsapp: 91-9075014125
product: tert -Butylamine
Inquiry

ASM Organics

Andhra Pradesh
Phone:91-9866122393
Whatsapp: 91-9866122393
product: tert -Butylamine
Inquiry

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.