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HomeProduct name listTenovin-6

Tenovin-6

  • CAS NO.:1011557-82-6
  • Empirical Formula: C25H34N4O2S
  • Molecular Weight: 454.63
  • MDL number: MFCD11976906
  • EINECS: 200-256-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-07-02 08:55:06
Tenovin-6 Structural

What is Tenovin-6?

The Uses of Tenovin-6

Tenovin-6 Hydrochloride, is a small molecule activator of p53 transcriptional activity. It acts as a potent SIRT1 and SIRT2 inhibitor as well.

What are the applications of Application

Tenovin-6 is an inhibitor of SIRT1, SIRT2, and SIRT3 and activator of p53

Definition

ChEBI: Tenovin-6 is a monocarboxylic acid amide obtained by formal condensation of the carboxy group of 5-(dimethylamino)pentanoic acid with the aromatic amino group of N-[(4-aminophenyl)carbamothioyl]-4-tert-butylbenzamide. It has a role as an antineoplastic agent, a Sir2 inhibitor and a p53 activator. It is a monocarboxylic acid amide, a member of thioureas and a tertiary amino compound.

Properties of Tenovin-6

Density  1.171±0.06 g/cm3(Predicted)
storage temp.  Store at -20° C
solubility  ≥22.75 mg/mL in DMSO; insoluble in H2O; ≥2.62 mg/mL in EtOH with ultrasonic
form  solid
pka 9.11±0.70(Predicted)
color  White to off-white

Safety information for Tenovin-6

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Tenovin-6

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