TEBIPENEM PIVOXIL
Synonym(s):(4R,5S,6S)-pivaloyloxymethyl 3-(1-(4,5-dihydrothiazol-2-yl)azetidin-3-ylthio)-6-((R)-1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylate;[4R-[4a,5?,6?(R*)]]-3-[[1-(4,5-dihydro-2-thiazolyl)-3-azetidinyl]thio]-6-(1-hydroxyethyl)-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid (2,2-dimethyl-1-oxopropoxy)methyl ester;TBM-PI;Tebi-pivoxil
- CAS NO.：161715-24-8
- Empirical Formula: C22H31N3O6S2
- Molecular Weight: 497.63
- MDL number: MFCD17215369
- EINECS: 1308068-626-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-08 09:03:02
What is TEBIPENEM PIVOXIL?
Chemical properties
White Solid
The Uses of TEBIPENEM PIVOXIL
Tebipenem pivoxil(L-084) is a novel oral carbapenem antibiotic with an IC50 of 100 μg/ml for human CYP isoforms. In mouse, rat, dog and monkey, TBPM-PI were absorbed quickly, and the bioavailability was (71.4, 59.1, 34.8 and 44.9%, respectively. There was
The Uses of TEBIPENEM PIVOXIL
Tebipenem Pivoxil is an oral carbapenem antibiotic. Tebipenem Pivoxil is absorbed and metabolized into Tebipenem, its active metabolite which showed excellent bactericidal activity against β-lactamase-nonproducing, ampicillin-resistant isolates.
Definition
ChEBI: Tebipenem pivoxil is a member of carbapenems and a pivaloyloxymethyl ester.
Properties of TEBIPENEM PIVOXIL
| Melting point: | 140-142℃ |
| Boiling point: | 661.9±65.0 °C(Predicted) |
| Density | 1.50 |
| storage temp. | Sealed in dry,Store in freezer, under -20°C |
| solubility | Chloroform (Slightly), DMSO (Slightly), Methanol (Slightly) |
| form | Solid |
| pka | 14.36±0.20(Predicted) |
| color | White |
Safety information for TEBIPENEM PIVOXIL
Computed Descriptors for TEBIPENEM PIVOXIL
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