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HomeProduct name listTALAMPICILLIN

TALAMPICILLIN

  • CAS NO.:47747-56-8
  • Empirical Formula: C24H23N3O6S
  • Molecular Weight: 481.52
  • MDL number: MFCD00869410
  • EINECS: 256-332-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-07-12 17:19:15
TALAMPICILLIN Structural

What is TALAMPICILLIN?

Originator

Talpen,Beecham,US,1975

The Uses of TALAMPICILLIN

Antibacterial.

Definition

ChEBI: Talampicillin is a penicillanic acid ester that is the 1-phthalidyl ester of ampicillin. It is a prodrug of ampicillin. It has a role as a prodrug. It is functionally related to an ampicillin and an o-phthalaldehydic acid.

Manufacturing Process

A fine suspension of 25.18 grams (0.05 mol) of potassium salt of enamine protected ampicillin and 10.65 grams (0.05 mol) 3-bromophthalide were reacted in a 1:2 mixture of acetone/ethyl acetate (1,500 ml) for 24 hours. After filtration the organic layer was washed twice with 250 ml portions of 1 N sodium bicarbonate and brine, dried over anhydrous magnesium sulfate and concentrated in vacuo. Addition of ether crystallized the phthalide enamine protected α-aminophenylacetamido penicillanate in 85% yield.

Therapeutic Function

Antibacterial

Properties of TALAMPICILLIN

Boiling point: 770.9±60.0 °C(Predicted)
Density  1.48±0.1 g/cm3(Predicted)
pka 12.15±0.60(Predicted)

Safety information for TALAMPICILLIN

Computed Descriptors for TALAMPICILLIN

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