sulforidazine
- CAS NO.:14759-06-9
- Empirical Formula: C21H26N2O2S2
- Molecular Weight: 402.57
- EINECS: 238-818-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-05-04 17:34:33
What is sulforidazine ?
Chemical properties
Thick Yellow Oil
Originator
Sulforidazine,ZYF Pharm Chemical
The Uses of sulforidazine
A major metabolite of Thioridazine (THD 2-SO2).
The Uses of sulforidazine
Thioridazine 2-Sulfone (Thioridazine EP Impurity E) is a major metabolite of Thioridazine (THD 2-SO2).
What are the applications of Application
Thioridazine 2-Sulfone is a major metabolite of Thioridazine
Definition
ChEBI: Sulforidazine is a member of phenothiazines.
Manufacturing Process
A mixture of 96.5 g 2-methylsulfonylphenothiazine, 50 g 2-(2-chloroethyl)-1- methylpiperidine, 62 g diethyl carbonate and 2 g sodium methylate was heated at 135°C for 1 hour and then at 180-190°C for 2.5 hours. The product was dissolved in benzene (500 ml) and the solution was extracted with 700 ml of 15% aqueous solution tartaric acid. The extract was washed with benzene. After addition of sodium carbonate solution to the extract was obtained a precipitate which was dissolved in benzene. This solution was washed with water and concentrated. 2-Methylsulfonyl-10-(2-(1-methyl-2- piperidyl)ethyl)phenothiazin was recrystallized from acetone, melting point 121-123°C.
Therapeutic Function
Neuroleptic
Properties of sulforidazine
Melting point: | 121-123° |
Boiling point: | 589.1±50.0 °C(Predicted) |
Density | 1?+-.0.06 g/cm3(Predicted) |
storage temp. | Refrigerator, Under Inert Atmosphere |
solubility | Acetonitrile (Slightly), Chloroform (Slightly), Methanol (Slightly) |
form | Solid |
pka | 9.83±0.10(Predicted) |
color | Off-White to Dark Yellow |
Safety information for sulforidazine
Computed Descriptors for sulforidazine
Related products of tetrahydrofuran
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