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HomeProduct name listSulfamonomethoxine

Sulfamonomethoxine

Synonym(s):N1-(6-Methoxy-4-pyrimidinyl)sulfanilamide;4-Amino-N-(6-methoxy-4-pyrimidinyl)benzenesulfonamide;4-Methoxy-6-sulfanilamidopyrimidine;SMM

  • CAS NO.:1220-83-3
  • Empirical Formula: C11H12N4O3S
  • Molecular Weight: 280.3
  • MDL number: MFCD00063466
  • EINECS: 624-483-8
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 20:33:22
Sulfamonomethoxine Structural

What is Sulfamonomethoxine?

Chemical properties

White To Off-White Crystalline Powder

The Uses of Sulfamonomethoxine

Protein binding. Inhibitor of enzyme. Sulfamonomethoxine and Trimethoprim

The Uses of Sulfamonomethoxine

antibacterial

The Uses of Sulfamonomethoxine

Protein binding. Inhibitor of enzyme. Sulfamonomethoxine and Trimethoprim are used for treating porcine unknown hyperpyrexia.

What are the applications of Application

Sulfamonomethoxine is an enzyme inhibitor used to address hyperpyrexia

Definition

ChEBI: Sulfamonomethoxine is a sulfonamide and a member of benzenes.

Synthesis Reference(s)

The Journal of Organic Chemistry, 26, p. 2764, 1961 DOI: 10.1021/jo01066a034

General Description

Chemical structure: sulfonamide

Biochem/physiol Actions

Sulfamonomethoxine is a competitive inhibitor of dihydropteroate synthetase used to block the synthesis of folic acid.

Properties of Sulfamonomethoxine

Melting point: 203-2060C
Boiling point: 513℃
Density  1.3936 (rough estimate)
refractive index  1.6200 (estimate)
Flash point: >110°(230°F)
storage temp.  Keep in dark place,Inert atmosphere,2-8°C
solubility  methanol: soluble10mg/mL
form  powder
pka pKa 5.94 (Uncertain)
color  white to white with yellow cast
Water Solubility  Soluble in water at 10mg/ml with warming. Also soluble in ethanol or methanol
BRN  621128
InChI InChI=1S/C11H12N4O3S/c1-18-11-6-10(13-7-14-11)15-19(16,17)9-4-2-8(12)3-5-9/h2-7H,12H2,1H3,(H,13,14,15)
CAS DataBase Reference 1220-83-3(CAS DataBase Reference)
EPA Substance Registry System Sulfamonomethoxine (1220-83-3)

Safety information for Sulfamonomethoxine

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H317:Sensitisation, Skin
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Sulfamonomethoxine

InChIKey WMPXPUYPYQKQCX-UHFFFAOYSA-N
SMILES C1(S(NC2C=C(OC)N=CN=2)(=O)=O)=CC=C(N)C=C1

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