Sulfadimethoxine
Synonym(s):4-Amino-N-(2,6-dimethoxy-4-pyrimidinyl)benzenesulfonamide;Sulfadimethoxine
- CAS NO.:122-11-2
- Empirical Formula: C12H14N4O4S
- Molecular Weight: 310.33
- MDL number: MFCD00057345
- EINECS: 204-523-7
- SAFETY DATA SHEET (SDS)
- Update Date: 2023-06-27 17:36:02
What is Sulfadimethoxine?
The Uses of Sulfadimethoxine
Antibacterial.
Background
Sulfadimethoxine is a sulfonamide antibiotic. Sulfadimethoxine is used to treat many infections, including treatment of respiratory, urinary tract, enteric, and soft tissue infections. It is most frequently used in veterinary medicine, although it is approved in some countries for use in humans. Sulfadimethoxine inhibits bacterial synthesis of folic acid (pteroylglutamic acid) from para-aminobenzoic acid. Sulfadimethoxine is approved in Russia for use in humans, including children, and has been successfully used there for more than 35 years. It is widely available in Russia as an over-the-counter drug manufactured by a number of Russian pharmaceutical companies.
In the US, sulfadimethoxine is one of the products that have been withdrawn or removed from the market after being found to be unsafe or not effective.
Indications
For use in the treatment of infections.
Pharmacokinetics
Sulfadimethoxine has been shown to be effective against streptococci, klebsiella, proteus, shigella, staphylococci, escherichia, and salmonella.
Metabolism
Not Available
Properties of Sulfadimethoxine
Melting point: | 200 °C |
Boiling point: | 265.5°C (rough estimate) |
Density | 1.4006 (rough estimate) |
storage temp. | Keep in dark place,Inert atmosphere,2-8°C |
solubility | NH4OH 1 M: 50 mg/mL, clear, faintly yellow |
form | neat |
color | White to Off-White |
Water Solubility | 46.3mg/L(37 ºC) |
Safety information for Sulfadimethoxine
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P501:Dispose of contents/container to..… |
Computed Descriptors for Sulfadimethoxine
Abamectin manufacturer
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