sphondin
- CAS NO.：483-66-9
- Empirical Formula: C12H8O4
- Molecular Weight: 216.19
- MDL number: MFCD00597230
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:55:10
What is sphondin?
Chemical properties
Off-white needle-like crystal, soluble in methanol, ethanol, DMSO and other organic solvents, derived from Oxtail Duhuo.
The Uses of sphondin
Sphondin has an Analgesic, anti-inflammatory, anti-allergic, smooth muscle spasmolytic effect.
Definition
ChEBI: Sphondin is a furanocoumarin.
Biological Activity
Sphondin, isolated from Heracleum laciniatum, has inhibitory effects on IL-1β-induced increases in COX-2 protein and PGE2 release levels in A549 cells.
in vitro
Pretreatment of A549 cells with Sphondin (10-50 μM) concentration-dependently attenuates IL-1β-induced COX-2 protein expression and PGE 2 release.
Properties of sphondin
| Melting point: | 189-191 °C |
| Boiling point: | 413.0±45.0 °C(Predicted) |
| Density | 1.368±0.06 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| form | Solid |
| color | Off-white to light yellow |
Safety information for sphondin
Computed Descriptors for sphondin
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