Sotorasib
- CAS NO.：2296729-00-3
- Empirical Formula: C30H30F2N6O3
- Molecular Weight: 560.61
- Update Date: 2024-05-24 17:10:14
What is Sotorasib?
Description
Sotorasib (AMG510) is a chiral compound and a potent KRAS G12C covalent inhibitor with potential antitumor activity.
The Uses of Sotorasib
Sotorasib (AMG510) is the first KRAS (G12C) inhibitor to enter clinical development. Having shown antitumor activity in clinical trials, AMG 510 represents a potentially transformative therapy.
Properties of Sotorasib
| Boiling point: | 730.5±70.0 °C(Predicted) |
| Density | 1.36±0.1 g/cm3(Predicted) |
| solubility | DMSO : 100 mg/mL (178.38 mM; Need ultrasonic)| |
| Water Solubility | Water : 33.33 mg/mL (59.46 mM; ultrasonic and adjust pH to 11 with NaOH) |
Safety information for Sotorasib
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for Sotorasib
Abamectin manufacturer
Bulat Pharmaceutical Pvt Ltd
1Y
Phone:+91-8448085660
Whatsapp: +91 8448085660
product: 2296729-00-3 Sotorasib AMG510 98%
Aspen Biopharma Labs Pvt Ltd
1Y
Phone:+91-9248058662
Whatsapp: +91-9248058662
product: Sotorasib 2252403-56-6 / 2296729-00-3 98%
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