Sitagliptin Impurity 12
- CAS NO.:1803026-54-1
- Empirical Formula: C16H12F6N4O
- Molecular Weight: 390.28
- Update Date: 2023-05-15 10:44:01
What is Sitagliptin Impurity 12?
The Uses of Sitagliptin Impurity 12
(2Z)-1-[5,6-Dihydro-3-(trifluoromethyl)-1,2,4-triazolo[4,3-a]pyrazin-7(8H)-yl]-4-(2,4,5-trifluorophenyl)-2-buten-1-one is an intermediate in the synthesis of 3-Desamino-2,3-dehydro Sitagliptin (D281985),an impurity of Sitagliptin (S491000). Sitagliptin is a trizolopyrazine dipeptidyl peptidase IV inhibitor. Sitagliptin has recently been approved for the therapy of type II diabetes.
Properties of Sitagliptin Impurity 12
Boiling point: | 517.5±60.0 °C(Predicted) |
Density | 1.52±0.1 g/cm3(Predicted) |
solubility | soluble in Chloroform, DCM, Methanol |
pka | -0.06±0.20(Predicted) |
form | Oil |
color | Light Yellow |
Safety information for Sitagliptin Impurity 12
Computed Descriptors for Sitagliptin Impurity 12
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
Methyl 3-Oxo-4-(2,4,5-trifluorophenyl)butanoate
Sitagliptin
Benzenebutanoicacid,b-[[(1,1-diMethylethoxy)carbonyl]aMino]-2,4,5-trifluoro-,Methylester,(bR)-
(R)-methyl 3-acetamido-4-(2,4,5-trifluorophenyl)butanoate
2,4,5-TRIFLUOROBENZYL CHLORIDE
Sitagliptin Impurity 34
2-CHLOROMETHYL-5-TRIFLUOROMETHYL-[1,3,4]OXADIAZOLE
ethyl 3-oxo-4-(2,4,5-trifluorophenyl)butanoate
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