Sevelamer carbonate
- CAS NO.:845273-93-0
- Empirical Formula: C7H14ClNO4
- Molecular Weight: 211.64
- MDL number: MFCD18904375
- EINECS: 682-521-9
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-11 17:04:31
What is Sevelamer carbonate?
Description
Sevelamer carbonate (SC) is a non-absorbed phosphate binding crosslinked polymer, with the same polymeric structure as sevelamer hydrochloride, in which carbonate replaces chloride as the counterion. SC has been found to have the same safety and efficacy profile as Sevelamer HCl in HD patients.
Sevelamer carbonate(Renvela) is a nonaluminum, non-calcium-basedphosphorus binder that traps phosphorus in the bowel through ion exchange and hydrogen binding. This drug replaced sevelamer hydrochloride(Renagel) and has an advantage of not generating an acid load, as its precursor, sevelamer hydrochloride, did. It also has the advantage of lowering LDL cholesterol due to gut binding of bile acids.
The Uses of Sevelamer carbonate
Sevelamer Carbonate, a non-?absorbed polymer is an oral phosphate binder in patients with kidney failure. It is reported that Sevelamer Carbonate is less likely to cause hypercalcemia, low levels of PTH, and progressive coronary and aortic calcification in hemodialysis patients than calcium-?based phosphate binders.
The Uses of Sevelamer carbonate
Control of serum phosphorus in patients with chronic kidney disease (phosphate binder).
Properties of Sevelamer carbonate
storage temp. | Room Temperature, under inert atmosphere |
solubility | <4.74mg/mL in DMSO |
form | Solid |
color | White to Pale Beige |
Safety information for Sevelamer carbonate
Computed Descriptors for Sevelamer carbonate
Abamectin manufacturer
Hem-Deep Organics Pvt. Ltd. (HOPL)
Sun Pharmaceutical Industries Ltd
SNJ Labs Pvt Ltd
Apothecon Pharmaceuticals Pvt Ltd
Anugraha Chemicals
Om Pharmaceutical Industries
Solara Active Pharma Sciences Ltd
New Products
(R)-(-)-2-Amino-1-propanol Tetrahydro-4H-pyran-4-one Bromine 99.5% AR (4 x 500ml) Linseed Oil Extrapure Hydrogen Sulphide Solution Oxalic Acid 0.05 mol/L (0.01N) Solution EDTA 0.1 mol/L (0.2N) for 1000 ml Ferroin 0.025M Solution AR 1,2,3,4-Tetrahydrocarbazol-4-one 4-Hydroxy Carbazole Amino Salicylic Acid. U.S.P. 2 – Methoxy – 5- Sulfamoyl Benzoic acid Acetone Isobutryl oxime ester Sodium Amino Salicylate Dihydrate (PAS Sodium) IP/BP/USP/EP Aloe vera extract 200x Withania somnifera (Ashwagandha Extract) Citrus bioflavonoids Extract Spirulina (Arthrospira platensis) Powder Trikatu Extract Thymol Oil Ethyl 3-(Pyridin-2-Ylamino)Propanoate Bilastine -IP/BP/ Cypermethric Acid Chloride 5-NitrosalicylaldehydeRelated products of tetrahydrofuran
You may like
-
Sevelamer carbonate 98%View Details
-
845273-93-0 98%View Details
845273-93-0 -
845273-93-0 Sevelamer carbonate 98%View Details
845273-93-0 -
845273-93-0 Sevelamer carbonate 99%View Details
845273-93-0 -
845273-93-0 99%View Details
845273-93-0 -
Sevelamer carbonate 99%View Details
845273-93-0 -
Sevelamer carbonate CAS 845273-93-0View Details
845273-93-0 -
845273-93-0 95-99%View Details
845273-93-0