Setiptiline

CAS NO.：57262-94-9
Empirical Formula: C19H19N
Molecular Weight: 261.36
MDL number: MFCD00868385
EINECS: 260-653-4
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-18 11:30:59

What is Setiptiline?

Description

Setiptiline is a mianserin analog reportedly useful in the treatment of depression with a favorable side-effect profile. It is a potent antagonist of alpha-receptors, with greater affinity at alpha, than alpha, sites, as well as an inhibitor of central serotonin receptors.

Originator

Organon (Netherlands)

The Uses of Setiptiline

Setiptiline is a tetracyclic antidepressant. Setiptiline acts as a noradrenergic and specific serotonergic antidepressant (NaSSA).

Definition

ChEBI: Setiptiline is a tetracyclic antidepressant that is 2,3,4,9-tetrahydro-1H-dibenzo[3,4:6,7]cyclohepta[1,2-c]pyridine carrying a methyl group at position 2. Its maleate salt is used for the treatment of depression in Japan. It has a role as an alpha-adrenergic antagonist and a serotonergic antagonist. It is a tetracyclic antidepressant and a tertiary amino compound. It is a conjugate base of a setiptiline(1+).

brand name

Tecipul

Properties of Setiptiline

Melting point:	>120°C (dec.)
Boiling point:	421.7±34.0 °C(Predicted)
Density	1.15
storage temp.	Sealed in dry,Store in freezer, under -20°C
solubility	DMSO (Slightly), Methanol (Slightly)
form	Solid
pka	8.34±0.20(Predicted)
color	White to Light Yellow