SDZWAG994
- CAS NO.：130714-47-5
- Empirical Formula: C17H25N5O4
- Molecular Weight: 363.41
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-01 18:44:47
What is SDZWAG994?
The Uses of SDZWAG994
Adenosine receptors are potential therapeutic targets for cerebral and cardiac ischaemic diseases, sleep disorders, immune and inflammatory disorders and cancer. N-Cyclohexyl-2''-O-methyladenosine is an inhibitor of adenosine deaminase-induced lipolysis and a selective adenosine A1-R agonist.
What are the applications of Application
SDZ WAG 994 is a selective Adenosine A1-R agonist
Biological Activity
Potent and selective A 1 adenosine receptor agonist (K i values are 23, > 10000 and 25000 nM for A 1 , A 2A and A 2B receptors respectively). Causes a sustained fall in blood pressure and heart rate in spontaneous hypertensive rats and inhibits adenosine deaminase-stimulated lipolysis in rat adipocytes (K i = 8 nM).
storage
Desiccate at +4°C
Properties of SDZWAG994
| storage temp. | Desiccate at +4°C |
| solubility | Soluble to 100 mM in 1.1eq. NaOH and to 100 mM in DMSO |
| form | Powder |
Safety information for SDZWAG994
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for SDZWAG994
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