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HomeProduct name listSCOULERIN

SCOULERIN

  • CAS NO.:6451-73-6
  • Empirical Formula: C19H21NO4
  • Molecular Weight: 327.37
  • MDL number: MFCD00221721
  • EINECS: 200-258-5
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-11-19 23:02:33
SCOULERIN Structural

What is SCOULERIN?

Description

This form of the alkaloid is more widespread than the d-form, occurring in Corydalis caseana, C. micrantha, C. montana, C. scouleri, C. sibirica and Papaver somniferum. It has [α]26D - 318° (c 0.41, MeOH) or - 289° (c 0.62, MeOH). It forms pale grey needles when crystallized from MeOH. The hydrochloride has m.p. 268-9°C; the picrate, m.p. 206°C (dec.) and the diethyl ether, m.p. 155°C. The oxidation products are the same as for the preceding base.

Chemical properties

Off-White to Pale Pink Solid

The Uses of SCOULERIN

(S)-Scoulerine is an alkaloid found in the opium poppy. (S)-Scoulerine acts as an antagonist at the α2-adrenoceptor, α1D-adrenoceptor and 5-HT receptor.

The Uses of SCOULERIN

The S-(+)-enantiomer of Scoulerine, an alkaloid found in the opium poppy.

What are the applications of Application

Scoulerin is Scoulerin is an alkaloid found in the opium poppy, Croton flavens, and certain plants in the Erythrina genus.

Definition

ChEBI: A berberine alkaloid isolated from Corydalis saxicola.

References

Manske., Can. J. Res., 14B, 347, 354 (1936)
Manske., ibid, 17B, 57 (1939)
Manske., ibid, 18B, 414 (1940)
Manske., ibid, 20B, 49 (1942)
Brochmann-Hanssen, Nielsen., Tetrahedron Lett., 2261 (1966)
Synthesis:
Kametani., Japanese Patent, 70, 37,976, 10 December 1970

Properties of SCOULERIN

Melting point: 192°C
Boiling point: 503.3±50.0 °C(Predicted)
Density  1.37±0.1 g/cm3(Predicted)
storage temp.  Store at -20°C
solubility  Soluble in DMSO
pka 9.88±0.20(Predicted)
form  A crystalline solid
color  Off-white to pink

Safety information for SCOULERIN

Computed Descriptors for SCOULERIN

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