SB 269970 HYDROCHLORIDE
Synonym(s):(R)-3-[2-[2-(4-Methylpiperidin-1-yl)ethyl]pyrrolidine-1-sulfonyl]phenol hydrochloride;SB 269970A
- CAS NO.：201038-74-6
- Empirical Formula: C18H28N2O3S
- Molecular Weight: 352.49
- MDL number: MFCD08056273
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-28 23:16:16
What is SB 269970 HYDROCHLORIDE?
The Uses of SB 269970 HYDROCHLORIDE
SB 269970 is a selective and potent SR-7 antagonist.
What are the applications of Application
SB 269970 hydrochloride is a selective and potent SR-7 antagonist
Definition
ChEBI: 3-[[(2R)-2-[2-(4-methyl-1-piperidinyl)ethyl]-1-pyrrolidinyl]sulfonyl]phenol is a sulfonamide.
Biological Activity
Potent and selective 5-HT 7 receptor antagonist (pK i values are 8.9, 7.2 and 6.0 for 5-HT 7A , 5-HT 5A and 5-HT 1B and < 6.0 for 5-HT 1A , 5-HT 1D , 5-HT 1E , 5-HT 1F , 5-HT 2A , 5-HT 2B , 5-HT 2C , 5-HT 4 and 5-HT 6 receptors respectively). Brain penetrant in vivo .
Properties of SB 269970 HYDROCHLORIDE
| Boiling point: | 512.9±56.0 °C(Predicted) |
| Density | 1.188 |
| storage temp. | Inert atmosphere,2-8°C |
| solubility | H2O: 22 mg/mL |
| form | solid |
| pka | 8.88±0.10(Predicted) |
Safety information for SB 269970 HYDROCHLORIDE
Computed Descriptors for SB 269970 HYDROCHLORIDE
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