safracin B

CAS NO.：87578-99-2
Empirical Formula: C28H36N4O7
Molecular Weight: 540.61
MDL number: MFCD01939882
SAFETY DATA SHEET (SDS)
Update Date: 2023-05-04 15:13:31

$safracin B Structural$

What is safracin B?

Description

Safracin B (87578-99-2) is a novel antibiotic of the saframycin family produced by?Pseudomonas fluorescens.1?Safracin B displays antitumor activity against L1210 and P388 leukemias and B16 melanoma. Compared with safracin A, the toxic and effective doses were much lower. Safracin B also prolonged the life of tumor-bearing mice to a greater extent than safracin A.2

The Uses of safracin B

Safracin B is a new antibiotics from the family of Safracin produced by Pseudomonas fluorescens A2-2. Safracin B is an antibiotic that exhibits anti-tumor properties.

References

1) Ikeda?et al.?(1983),?Safracins, new antitumor antibiotics. I. Producing organism, fermentation and isolation; J. Antibiot. Tokyo,?36?1279 2) Okumoto?et al. (1985),?Activity of safracins A and B, heterocyclic quinone antibiotics, on experimental tumors in mice; J. Antibiot.Tokyo,?38?767

Properties of safracin B

Boiling point:	755.1±60.0 °C(Predicted)
Density	1.41±0.1 g/cm3(Predicted)
storage temp.	-20°C
solubility	Soluble in DMSO (up to 20 mg/ml)
pka	9.75±0.70(Predicted)
form	solid
color	Yellow-green
Stability:	Stable for 1 year from date of purchase as supplied. Solutions in DMSO may be stored at -20°C for up to 3 months.