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HomeProduct name listS-ETHYL TRIFLUOROTHIOACETATE

S-ETHYL TRIFLUOROTHIOACETATE

  • CAS NO.:383-64-2
  • Empirical Formula: C4H5F3OS
  • Molecular Weight: 158.14
  • MDL number: MFCD00000421
  • EINECS: 206-852-1
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2023-06-08 17:06:38
S-ETHYL TRIFLUOROTHIOACETATE Structural

What is S-ETHYL TRIFLUOROTHIOACETATE?

Chemical properties

clear colorless to slightly yellow liquid

The Uses of S-ETHYL TRIFLUOROTHIOACETATE

S-Ethyl trifluorothioacetate was used to selectively trifluoroacetylate amino groups in proteins.

What are the applications of Application

S-Ethyl trifluorothioacetate is a trifluoroacetylating agent

Synthesis Reference(s)

Journal of the American Chemical Society, 74, p. 4005, 1952 DOI: 10.1021/ja01136a010

Purification Methods

If IR is free of OH bands then fractionally distil it; otherwise dilute the thio-ester with dry Et2O, wash with 5% KOH and H2O, dry over MgSO4 and fractionate it through an efficient column [Hauptschein et al. J Am Chem Soc 74 4005 1952]. [Beilstein 2 IV 567.] Powerful obnoxious odour.

Properties of S-ETHYL TRIFLUOROTHIOACETATE

Boiling point: 90.5 °C(lit.)
Density  1.234 g/mL at 25 °C(lit.)
refractive index  n20/D 1.376(lit.)
Flash point: 39 °F
storage temp.  Store at RT.
form  clear liquid
color  Colorless to Light yellow
BRN  1761564
CAS DataBase Reference 383-64-2(CAS DataBase Reference)
EPA Substance Registry System Ethanethioic acid, trifluoro-, S-ethyl ester (383-64-2)

Safety information for S-ETHYL TRIFLUOROTHIOACETATE

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
GHS Hazard Statements H225:Flammable liquids
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233:Keep container tightly closed.
P240:Ground/bond container and receiving equipment.
P241:Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242:Use only non-sparking tools.
P243:Take precautionary measures against static discharge.

Computed Descriptors for S-ETHYL TRIFLUOROTHIOACETATE

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