(S)-(+)-Epichlorohydrin
Synonym(s):(S)-(+)-2-(Chloromethyl)oxirane;1-Chloro-2,3-epoxypropane, 2-Chloromethyl oxirane, 2,3-Epoxypropyl chloride;Epichlorohydrine
- CAS NO.:67843-74-7
- Empirical Formula: C3H5ClO
- Molecular Weight: 92.52
- MDL number: MFCD00077760
- EINECS: 614-150-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-22 13:59:06
What is (S)-(+)-Epichlorohydrin?
Chemical properties
Epichlorhydrin is a colourless liquid with odour, b.p. 115°C.
The Uses of (S)-(+)-Epichlorohydrin
(S)-(+)-Epichlorohydrin is utilized for the synthesis of macquarimicins and hydroxyisoxazolidines and (+)-cis-sylvaticin, which is a potential antitumor agent. It is used to synthesize inhibitors of fatty acid oxidation as potential metabolic modulators. It acts as a solvent for natural and synthetic resins, gums, cellulose esters and ethers, paints, varnishes, nail enamels, lacquers and cement for celluloid. It is also used as a stabilizer and also useful as a bifunctional alkylating agent with the potential to form DNA cross-links.
The Uses of (S)-(+)-Epichlorohydrin
S-enantiomer of Epichlorohydrin, (S)-Epichlorohydrin), an important industrial chemical, is a bifunctional alkylating agent with the potential to form DNA cross-links. It is used as a solvent for natural and synthetic resins, gums, cellulose esters and ethers, paints, varnishes, nail enamels and lacquers, cement for Celluloid. Also, it is used as stabilizer.
Definition
ChEBI: (S)-epichlorohydrin is an epichlorohydrin. It is functionally related to a (R)-1,2-epoxypropane. It is an enantiomer of a (R)-epichlorohydrin.
Synthesis
(S)-(+)-Epichlorohydrin is a chlorohydrin that is used as an industrial chemical. It can be synthesized by reacting benzyl chloride with sodium hydroxide in the presence of water.
Properties of (S)-(+)-Epichlorohydrin
Melting point: | −57 °C(lit.) |
Boiling point: | 92-93 °C360 mm Hg(lit.) |
alpha | 34 º (589nm, c=1, MeOH) |
Density | 1.183 g/mL at 25 °C(lit.) |
vapor density | 3.2 (vs air) |
vapor pressure | 13.8 mm Hg ( 21.1 °C) |
refractive index | n |
Flash point: | 93 °F |
storage temp. | Inert atmosphere,2-8°C |
solubility | Chloroform, Methanol (Slightly) |
form | Liquid |
color | Clear colorless to very pale yellow |
explosive limit | 21% |
optical activity | [α]20/D +35°, c = 1 in methanol |
Water Solubility | insoluble |
BRN | 1420784 |
Dielectric constant | 22.9(20℃) |
CAS DataBase Reference | 67843-74-7(CAS DataBase Reference) |
Safety information for (S)-(+)-Epichlorohydrin
Signal word | Danger |
Pictogram(s) |
Flame Flammables GHS02 Corrosion Corrosives GHS05 Skull and Crossbones Acute Toxicity GHS06 Health Hazard GHS08 |
GHS Hazard Statements |
H226:Flammable liquids H314:Skin corrosion/irritation H317:Sensitisation, Skin H350:Carcinogenicity |
Precautionary Statement Codes |
P202:Do not handle until all safety precautions have been read and understood. P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P280:Wear protective gloves/protective clothing/eye protection/face protection. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for (S)-(+)-Epichlorohydrin
(S)-(+)-Epichlorohydrin manufacturer
JSK Chemicals
New Products
(S)-3-Aminobutanenitrile hydrochloride 4-Methylphenylacetic acid N-Boc-D-alaninol N-BOC-D/L-ALANINOL Tert-butyl bis(2-chloroethyl)carbamate 3-Morpholino-1-(4-nitrophenyl)-5,6-dihydropyridin- 2(1H)-one Furan-2,5-Dicarboxylic Acid Tropic acid 1-Bromo-3,5-Di-Tert-Butylbenzene S-2-CHLORO PROPIONIC ACID ETHYL ISOCYANOACETATE 2-Bromo-1,3-Bis(Dimethylamino)Trimethinium Hexafluorophosphate 4-IODO BENZOIC ACID 3-NITRO-2-METHYL ANILINE 1-(2,4-DICHLOROPHENYL) ETHANAMINE (2-Hydroxyphenyl)acetonitrile 4-Bromopyrazole 2-(Cyanocyclohexyl)acetic acid 4-methoxy-3,5-dinitropyridine 1-(4-(aminomethyl)benzyl)urea hydrochloride 2-aminopropyl benzoate hydrochloride diethyl 2-(2-((tertbutoxycarbonyl)amino) ethyl)malonate tert-butyl 4- (ureidomethyl)benzylcarbamate Ethyl-2-chloro((4-methoxyphenyl)hydrazono)acetateRelated products of tetrahydrofuran
You may like
-
Epichlorohydrine 98%View Details
-
(S)-(+)-EPICHLOROHYDRIN 67843-74-7 99%View Details
67843-74-7 -
(S)-(+)-Epichlorohydrine CAS 67843-74-7View Details
67843-74-7 -
67843-74-7 S-Epichlorohydrin 99%View Details
67843-74-7 -
(S)-Epichlorohydrin 98%View Details
-
S-EPICHLOROHYDRIN 99%View Details
-
(S)-(+)-Epichlorohydrin CAS 67843-74-7View Details
67843-74-7 -
(S)-Epichlorohydrin CAS 67843-74-7View Details
67843-74-7