(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine

The Uses of (R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine

Intermediate in the production of (R)-Cetirizine (C281106).

The Uses of (R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine

(R)-1-[alpha-(4-Chlorophenyl)benzyl]piperazine intermediate in the production of (R)-Cetirizine.

What are the applications of Application

(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine is Intermediate in the production of (R)-Cetirizine

What are the applications of Application

(R)-1-[(4-Chlorophenyl)phenylmethyl]piperazine could be used to synthesize a series of novel derivatives. Most of these derivatives significantly affected both allergic asthma and allergic itching. Meanwhile, in the test of allergic itching, five of the 19 compounds have more potent activities than levocetirizine[1].

References

[1] Lisheng Wang. “Design, synthesis, and anti-allergic activities of novel (R)(-)-1-[(4-chlorophenyl)phenyl methyl]piperazine derivatives.” Medicinal Chemistry Research 21 1 (2010): 124–132.