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HomeProduct name listS-ACETYLMERCAPTOSUCCINIC ANHYDRIDE

S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE

Synonym(s):2-(Acetylthio)succinic anhydride;SAMSA

  • CAS NO.:6953-60-2
  • Empirical Formula: C6H6O4S
  • Molecular Weight: 174.17
  • MDL number: MFCD00005526
  • EINECS: 230-135-2
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2022-11-11 11:01:00
S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE Structural

What is S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE?

General Description

S-Acetylmercaptosuccinic anhydride is an amine reactive reagent, containing a sulfhydryl group. The anhydride region opens up, when attacked by an amine nucleophile, forming amine linkage. However, during this ring opening reaction, a free carboxylate group is formed rendering the molecule negatively charged. Activity to proteins and conformation of the molecule us affected by the charge reversal.

Properties of S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE

Melting point: 83-86 °C (lit.)
Boiling point: 354.3±31.0 °C(Predicted)
Density  1.42±0.1 g/cm3(Predicted)
storage temp.  2-8°C
Sensitive  Hygroscopic
CAS DataBase Reference 6953-60-2(CAS DataBase Reference)
EPA Substance Registry System Ethanethioic acid, S-(tetrahydro-2,5-dioxo-3-furanyl) ester (6953-60-2)

Safety information for S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P264:Wash hands thoroughly after handling.
P264:Wash skin thouroughly after handling.
P271:Use only outdoors or in a well-ventilated area.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for S-ACETYLMERCAPTOSUCCINIC ANHYDRIDE

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