Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list(S)-5-Hydroxymethyldihydrofuran-2-one

(S)-5-Hydroxymethyldihydrofuran-2-one

Synonym(s):(S)-γ-Hydroxymethyl-γ-butyrolactone;(S)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone;(S)-5-Hydroxymethyl-2-oxotetrahydrofuran

(S)-5-Hydroxymethyldihydrofuran-2-one Structural

What is (S)-5-Hydroxymethyldihydrofuran-2-one?

Chemical properties

Colorless to light yellow liqui

The Uses of (S)-5-Hydroxymethyldihydrofuran-2-one

(S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone can be used as a chiral synthon to synthesize:

  • Potent nucleoside, acetylcholine, and (+)-muricatacin analogs.
  • Mevinic acids, which are LDL cholesterol-lowering agents.
  • Adenine based anti-HIV agent named β-F-ddA.

What are the applications of Application

(S)-(+)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone is a versatile chiral synthon employed in the synthesis of natural and unnatural products

General Description

Dihydro-5-(hydroxymethyl)-2(3H)-furanone is a chiral building block widely used in the synthesis of many natural products and few biologically significant compounds like anti-HIV dideoxynucleosides. It is also used in the synthesis of optically active ligands.

Properties of (S)-5-Hydroxymethyldihydrofuran-2-one

Melting point: 72-74 °C
Boiling point: 110-115 °C/0.2 mmHg (lit.)
alpha  56 º (c=3 in chloroform)
Density  1.237 g/mL at 25 °C (lit.)
refractive index  n20/D 1.471(lit.)
Flash point: >230 °F
storage temp.  2-8°C
form  clear liquid
pka 14.12±0.10(Predicted)
color  Colorless to Almost colorless
optical activity [α]20/D +56°, c = 3 in chloroform
BRN  1680284
CAS DataBase Reference 32780-06-6(CAS DataBase Reference)
NIST Chemistry Reference (S)-(+)-2',3'-dideoxyribonolactone(32780-06-6)

Safety information for (S)-5-Hydroxymethyldihydrofuran-2-one

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P302+P352:IF ON SKIN: wash with plenty of soap and water.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P332+P313:IF SKIN irritation occurs: Get medical advice/attention.
P337+P313:IF eye irritation persists: Get medical advice/attention.

Computed Descriptors for (S)-5-Hydroxymethyldihydrofuran-2-one

Related products of tetrahydrofuran

You may like

  • (S)-(+)-γ-Hydroxymethyl-γ-butyrolactone, 95% CAS 32780-06-6
    (S)-(+)-γ-Hydroxymethyl-γ-butyrolactone, 95% CAS 32780-06-6
    32780-06-6
    View Details
  • (S)-(+)-γ-Hydroxymethyl-γ-butyrolactone CAS 32780-06-6
    (S)-(+)-γ-Hydroxymethyl-γ-butyrolactone CAS 32780-06-6
    32780-06-6
    View Details
  • 1823368-42-8 98%
    1823368-42-8 98%
    1823368-42-8
    View Details
  • 2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    2-(3-(tert-butyl)phenoxy)-2-methylpropanoic acid 1307449-08-6 98%
    1307449-08-6
    View Details
  • Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    Ethyl 3-(furan-2-yl)-3-hydroxypropanoate 25408-95-1 98%
    25408-95-1
    View Details
  • 2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    2-Chloro-5-fluoro-1-methoxy-3-methylbenzene 98%
    1805639-70-6
    View Details
  • 1784294-80-9 98%
    1784294-80-9 98%
    1784294-80-9
    View Details
  • Lithium Clavulanate
    Lithium Clavulanate
    61177-44-4
    View Details
Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.