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HomeProduct name list2,3-Dihydrofuran

2,3-Dihydrofuran

Synonym(s):2,3-DHF

  • CAS NO.:1191-99-7
  • Empirical Formula: C4H6O
  • Molecular Weight: 70.09
  • MDL number: MFCD00003205
  • EINECS: 214-747-7
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-12-18 14:08:52
2,3-Dihydrofuran Structural

What is 2,3-Dihydrofuran?

Chemical properties

clear colourless liquid

The Uses of 2,3-Dihydrofuran

2,3-Dihydrofuran is a dehydration product of tetrahydrofuran (THF). 2,3-Dihydrofuran is also used in the preparation of niologically active compounds such as antitumor agents.

The Uses of 2,3-Dihydrofuran

2,3-Dihydrofuran is a versatile reagent used in lanthanide-catalyzed Diels-Alder reactions with 2-pyrones and in Rh(II)-stabilized cycloadditions with vinylcarbenoids. It is applied for alkylation by active methylene compounds, catalyzed by trans-Dichlorobis(triphenyl-phosphine)-palladium(II). It is also used in the preparation of biologically active compounds such as antitumor agents.

What are the applications of Application

2,3-Dihydrofuran is a versatile synthesis reagent

Definition

ChEBI: 2,3-dihydrofuran is a dihydrofuran.

General Description

The enantioselective Heck arylation of 2,3-dihydrofuran with aryl iodides was studied.

Properties of 2,3-Dihydrofuran

Melting point: 280 °C(Solv: trichloroethylene (79-01-6); ethanol (64-17-5))
Boiling point: 54-55 °C (lit.)
Density  0.927 g/mL at 25 °C (lit.)
vapor pressure  14.46 psi ( 55 °C)
refractive index  n20/D 1.423(lit.)
Flash point: −12 °F
storage temp.  2-8°C
solubility  soluble in Chloroform
form  Liquid
color  Clear colorless
Water Solubility  slightlu soluble
BRN  103168
CAS DataBase Reference 1191-99-7(CAS DataBase Reference)
NIST Chemistry Reference Furan, 2,3-dihydro-(1191-99-7)
EPA Substance Registry System Furan, 2,3-dihydro- (1191-99-7)

Safety information for 2,3-Dihydrofuran

Signal word Danger
Pictogram(s)
ghs
Flame
Flammables
GHS02
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H225:Flammable liquids
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking.
P233:Keep container tightly closed.
P240:Ground/bond container and receiving equipment.
P241:Use explosion-proof electrical/ventilating/lighting/…/equipment.
P242:Use only non-sparking tools.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for 2,3-Dihydrofuran

InChIKey JKTCBAGSMQIFNL-UHFFFAOYSA-N

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