2,3-Dihydrofuran

Synonym(s):2,3-DHF

CAS NO.：1191-99-7
Empirical Formula: C4H6O
Molecular Weight: 70.09
MDL number: MFCD00003205
EINECS: 214-747-7
SAFETY DATA SHEET (SDS)
Update Date: 2025-01-27 09:38:02

What is 2,3-Dihydrofuran?

Chemical properties

clear colourless liquid

The Uses of 2,3-Dihydrofuran

2,3-Dihydrofuran is a dehydration product of tetrahydrofuran (THF). 2,3-Dihydrofuran is also used in the preparation of niologically active compounds such as antitumor agents.

The Uses of 2,3-Dihydrofuran

2,3-Dihydrofuran is a versatile reagent used in lanthanide-catalyzed Diels-Alder reactions with 2-pyrones and in Rh(II)-stabilized cycloadditions with vinylcarbenoids. It is applied for alkylation by active methylene compounds, catalyzed by trans-Dichlorobis(triphenyl-phosphine)-palladium(II). It is also used in the preparation of biologically active compounds such as antitumor agents.

What are the applications of Application

2,3-Dihydrofuran is a versatile synthesis reagent

Definition

ChEBI: 2,3-dihydrofuran is a dihydrofuran.

General Description

The enantioselective Heck arylation of 2,3-dihydrofuran with aryl iodides was studied.

Properties of 2,3-Dihydrofuran

Melting point:	280 °C(Solv: trichloroethylene (79-01-6); ethanol (64-17-5))
Boiling point:	54-55 °C (lit.)
Density	0.927 g/mL at 25 °C (lit.)
vapor pressure	14.46 psi ( 55 °C)
refractive index	n20/D 1.423(lit.)
Flash point:	−12 °F
storage temp.	2-8°C
solubility	soluble in Chloroform
form	Liquid
color	Clear colorless
Water Solubility	slightlu soluble
BRN	103168
CAS DataBase Reference	1191-99-7(CAS DataBase Reference)
NIST Chemistry Reference	Furan, 2,3-dihydro-(1191-99-7)
EPA Substance Registry System	Furan, 2,3-dihydro- (1191-99-7)

Safety information for 2,3-Dihydrofuran

Signal word	Danger
Pictogram(s)	Flame Flammables GHS02 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H225:Flammable liquids H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P210:Keep away from heat/sparks/open flames/hot surfaces. — No smoking. P233:Keep container tightly closed. P240:Ground/bond container and receiving equipment. P241:Use explosion-proof electrical/ventilating/lighting/…/equipment. P242:Use only non-sparking tools. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.