(S)-(-)-5-FLUOROWILLARDIINE

CAS NO.：140187-23-1
Empirical Formula: C7H8FN3O4
Molecular Weight: 217.15
MDL number: MFCD00153880
SAFETY DATA SHEET (SDS)
Update Date: 2024-10-30 18:52:02

What is (S)-(-)-5-FLUOROWILLARDIINE?

The Uses of (S)-(-)-5-FLUOROWILLARDIINE

(S)-(-)-5-Fluorowillardiine is a potent and selective AMPA receptor agonist at hGluR1 and hGluR2 (1,2).

What are the applications of Application

(S)-(?)-5-Fluorowillardiine is an extremely potent and selective AMPA receptor agonist at hGluR1 and hGluR2

Definition

ChEBI: An alanine derivative that is L-alanine bearing a 5-fluorouracil-1-yl substituent at position 3. A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (Ki = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively).

Biological Activity

A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (K i = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively). Also available as part of the AMPA Receptor Tocriset™ .

Properties of (S)-(-)-5-FLUOROWILLARDIINE

Melting point:	>209°C (dec.)
storage temp.	Sealed in dry,Room Temperature
solubility	Aqueous Acid (Slightly)
form	Solid
color	White to Pale Beige

Safety information for (S)-(-)-5-FLUOROWILLARDIINE

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.