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HomeProduct name list(S)-(-)-5-FLUOROWILLARDIINE

(S)-(-)-5-FLUOROWILLARDIINE

(S)-(-)-5-FLUOROWILLARDIINE Structural

What is (S)-(-)-5-FLUOROWILLARDIINE?

The Uses of (S)-(-)-5-FLUOROWILLARDIINE

(S)-(-)-5-Fluorowillardiine is a potent and selective AMPA receptor agonist at hGluR1 and hGluR2 (1,2).

What are the applications of Application

(S)-(?)-5-Fluorowillardiine is an extremely potent and selective AMPA receptor agonist at hGluR1 and hGluR2

Definition

ChEBI: An alanine derivative that is L-alanine bearing a 5-fluorouracil-1-yl substituent at position 3. A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (Ki = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively).

Biological Activity

A more potent and selective AMPA receptor agonist (at hGluR1 and hGluR2) than AMPA itself (K i = 14.7, 25.1, and 1820 nM for hGluR1, hGluR2 and hGluR5 respectively). Also available as part of the AMPA Receptor Tocriset™ .

Properties of (S)-(-)-5-FLUOROWILLARDIINE

Melting point: >209°C (dec.)
storage temp.  Sealed in dry,Room Temperature
solubility  Aqueous Acid (Slightly)
form  Solid
color  White to Pale Beige

Safety information for (S)-(-)-5-FLUOROWILLARDIINE

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H302:Acute toxicity,oral
H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for (S)-(-)-5-FLUOROWILLARDIINE

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