(S)-(-)-4-Bromo-alpha-phenylethylamine

Synonym(s):(S)-(−)-4-Bromo-α-methylbenzylamine

CAS NO.：27298-97-1
Empirical Formula: C8H10BrN
Molecular Weight: 200.08
MDL number: MFCD00066026
EINECS: 608-076-2
SAFETY DATA SHEET (SDS)
Update Date: 2023-06-12 13:24:31

(S)-(-)-4-Bromo-alpha-phenylethylamine Structural

What is (S)-(-)-4-Bromo-alpha-phenylethylamine?

Chemical properties

clear colorless to light yellow liquid

The Uses of (S)-(-)-4-Bromo-alpha-phenylethylamine

(S)-(-)-1-(4-Bromophenyl)ethylamine is utilized as an important raw material in organic synthesis. It also serves as an intermediate in organic synthesis and pharmaceuticals and agrochemicals.

The Uses of (S)-(-)-4-Bromo-alpha-phenylethylamine

(S)-(-)-1-(4-Bromophenyl)ethylamine may be used in the synthesis of (S)-1-(1-(4-bromophenyl) ethyl)-2-cyano-3-(quinoline-5-yl) guanidine, which is an intermediate to prepare a potent and selective antagonist and radioligand for rat P2X7 receptors.

Properties of (S)-(-)-4-Bromo-alpha-phenylethylamine

Melting point:	-25°C
Boiling point:	63-72 °C (0.2 mmHg)
alpha	-18 º (c=2,CH3OH)
Density	1.390 g/mL at 20 °C(lit.)
refractive index	n20/D 1.566
Flash point:	>110°C
storage temp.	under inert gas (nitrogen or Argon) at 2–8 °C
form	clear liquid
pka	8.82±0.10(Predicted)
color	Colorless to Almost colorless
optical activity	[α]20/D 20.5±1°, c = 3% in methanol
Sensitive	Air Sensitive
BRN	5729988
CAS DataBase Reference	27298-97-1(CAS DataBase Reference)

Safety information for (S)-(-)-4-Bromo-alpha-phenylethylamine

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07 Environment GHS09
GHS Hazard Statements	H314:Skin corrosion/irritation H317:Sensitisation, Skin H411:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P273:Avoid release to the environment. P280:Wear protective gloves/protective clothing/eye protection/face protection. P301+P312:IF SWALLOWED: call a POISON CENTER or doctor/physician IF you feel unwell. P303+P361+P353:IF ON SKIN (or hair): Remove/Take off Immediately all contaminated clothing. Rinse SKIN with water/shower. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.