(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

Synonym(s):α,α-Diphenyl-L-prolinol methylboronic acid cycl-amide ester;(S)-1-Methyl-3,3-diphenyl-tetrahydro-pyrrolo[1,2c][1,3,2]oxazaborole;(S)-3,3-Diphenyl-1-methyltetrahydro-3H-pyrrolo[1,2-c][1,3,2]oxazaborole;(S)-Tetrahydro-1-methyl-3,3-diphenyl-1H,3H-pyrrolo[1,2-c][1,3,2]oxazaborole

CAS NO.：112022-81-8
Empirical Formula: C18H20BNO
Molecular Weight: 277.17
MDL number: MFCD00078439
EINECS: 601-150-5
SAFETY DATA SHEET (SDS)
Update Date: 2023-04-23 13:52:06

(S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole Structural

What is (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole?

Chemical properties

Colorless to yellow liquid

The Uses of (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

suzuki reaction

The Uses of (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

(S)-2-Methyl-CBS-oxazaborolidine is used as an oxazaborolidine catalyst. It is also employed in the asymmetric reduction of prochiral ketones. Other applications include the enantioselective synthesis of α-hydroxy acids, α-amino acids, C2-symmetrical ferrocenyl diols and propargyl alcohols. It is an anhydrous catalyst for 'CBS' reduction reaction.

What are the applications of Application

(S)-(?)-2-Methyl-CBS-oxazaborolidine is an oxazaborolidine catalyst

Properties of (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

Melting point:	115-117°C
Boiling point:	111 °C
Density	0.93 g/mL at 20 °C(lit.)
refractive index	-68 ° (C=1, MeOH)
Flash point:	40 °F
storage temp.	room temp
form	Liquid
pka	1.02±0.40(Predicted)
color	Colorless to amber
Water Solubility	Hydrolyzes in water.
Sensitive	Air & Moisture Sensitive
BRN	8492123
Exposure limits	ACGIH: TWA 20 ppm OSHA: Ceiling 300 ppm; TWA 200 ppm NIOSH: IDLH 500 ppm; TWA 100 ppm(375 mg/m3); STEL 150 ppm(560 mg/m3)
CAS DataBase Reference	112022-81-8(CAS DataBase Reference)

Safety information for (S)-3,3-Diphenyl-1-methylpyrrolidino[1,2-c]-1,3,2-oxazaborole

Signal word	Danger
Pictogram(s)	Corrosion Corrosives GHS05 Exclamation Mark Irritant GHS07
GHS Hazard Statements	H302:Acute toxicity,oral H318:Serious eye damage/eye irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection.