Contact us: +91 9550333722 040 - 40102781
Structured search
India
Choose your country
Different countries will display different contents
Try our best to find the right business for you.
My chemicalbook

Welcome back!

HomeProduct name list(S)-(-)-2-Methyl-2-propanesulfinamide

(S)-(-)-2-Methyl-2-propanesulfinamide

  • CAS NO.:343338-28-3
  • Empirical Formula: C4H11NOS
  • Molecular Weight: 121.2
  • MDL number: MFCD05861480
  • EINECS: 640-158-3
  • SAFETY DATA SHEET (SDS)
  • Update Date: 2024-10-25 16:21:11
(S)-(-)-2-Methyl-2-propanesulfinamide Structural

What is (S)-(-)-2-Methyl-2-propanesulfinamide?

Physical properties

white to light yellow crystal powder

The Uses of (S)-(-)-2-Methyl-2-propanesulfinamide

(S)-(-)-2-Methyl-2-propanesulfinamide is used in Suzuki reaction. It is also employed as a reagent for synthesizing chiral amines. It acts as a chiral auxiliary used in an asymmetric synthesis of trifluoroethylamines by conversion of trifluoroacetaldehyde to a chiral imine. It is also involved in the transformation of P,N-sulfinyl imine ligands through condensation with aldehydes and ketones, which can undergo iridium-catalyzed asymmetric hydrogenation of olefins. Further, it serves as a reagent for the preparation of chemicals and pharmaceutical intermediates.

The Uses of (S)-(-)-2-Methyl-2-propanesulfinamide

(S)-(-)-2-Methyl-2-propanesulfinamide may be used to develop benzofuran-based farnesyltransferase inhibitors as anti-cancer agents. It may also be used to prepare (20E)-N-[t-butyl-(S)-sulfinyl]-3β-(t-butyldimethylsilyloxy)-pregn-5-en-20-imine, an intermediate for the preparation of androgen receptor antagonists.

Properties of (S)-(-)-2-Methyl-2-propanesulfinamide

Melting point: 97-101 °C(lit.)
Boiling point: 220.0±23.0 °C(Predicted)
alpha  -4.5 º (c=1, CHCl3)
Density  1.124
storage temp.  2-8°C
solubility  Chloroform (Slightly), Methanol (Slightly)
form  Crystalline Powder
pka 10.11±0.50(Predicted)
color  White
optical activity [α]20/D 4.5°, c = 1 in chloroform
Stability: store cold
InChI InChI=1/C4H11NOS/c1-4(2,3)7(5)6/h5H2,1-3H3/t7-/s3
CAS DataBase Reference 343338-28-3(CAS DataBase Reference)

Safety information for (S)-(-)-2-Methyl-2-propanesulfinamide

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H315:Skin corrosion/irritation
H319:Serious eye damage/eye irritation
H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes P261:Avoid breathing dust/fume/gas/mist/vapours/spray.
P280:Wear protective gloves/protective clothing/eye protection/face protection.
P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.
P405:Store locked up.

Computed Descriptors for (S)-(-)-2-Methyl-2-propanesulfinamide

InChIKey CESUXLKAADQNTB-SSDOTTSWSA-N
SMILES CC(C)([S@@](N)=O)C |&1:3,r|

Related products of tetrahydrofuran

You may like

Statement: All products displayed on this website are only used for non medical purposes such as industrial applications or scientific research, and cannot be used for clinical diagnosis or treatment of humans or animals. They are not medicinal or edible.