(S)-(+)-4-Phenyl-2-oxazolidinone
- CAS NO.:99395-88-7
- Empirical Formula: C9H9NO2
- Molecular Weight: 163.17
- MDL number: MFCD00043396
- EINECS: 619-429-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-08-21 22:41:43
What is (S)-(+)-4-Phenyl-2-oxazolidinone?
Chemical properties
white to light yellow crystal powde
The Uses of (S)-(+)-4-Phenyl-2-oxazolidinone
(S)-(+)-4-Phenyl-2-oxazolidinone is an intermediate for the synthesis and development for cholesterol absorption inhibitor AZD4121.
Description
(S)-(+)-4-Phenyl-2-oxazolidinone is a chiral auxiliary employed in the enantioselective synthesis of β-lactams Used as recyclable derivatizing agent for the chromatographic resolution of primary amines via allophanates.
Properties of (S)-(+)-4-Phenyl-2-oxazolidinone
Melting point: | 129-132 °C(lit.) |
Boiling point: | 290.25°C (rough estimate) |
alpha | 49.5 º (c=2, CHCl3) |
Density | 1.2021 (rough estimate) |
refractive index | 72 ° (C=1, AcOEt) |
storage temp. | Inert atmosphere,Room Temperature |
solubility | Chloroform (Slightly), Methanol (Slightly) |
form | Crystalline Powder |
pka | 12.05±0.40(Predicted) |
color | White |
optical activity | [α]20/D +48°, c = 2 in chloroform |
BRN | 131918 |
CAS DataBase Reference | 99395-88-7(CAS DataBase Reference) |
Safety information for (S)-(+)-4-Phenyl-2-oxazolidinone
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. |
Computed Descriptors for (S)-(+)-4-Phenyl-2-oxazolidinone
InChIKey | QDMNNMIOWVJVLY-MRVPVSSYSA-N |
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