Rosiglitazone hydrochloride
- CAS NO.：302543-62-0
- Empirical Formula: C18H20ClN3O3S
- Molecular Weight: 393.89
- MDL number: MFCD04112701
- EINECS: 1308068-626-2
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-29 14:36:51
What is Rosiglitazone hydrochloride?
Chemical properties
Rosiglitazone is a hypoglycemic drug developed by GS, and the revalent compounds are disclosed in European Patent EP 306228.
The Uses of Rosiglitazone hydrochloride
Rosiglitazone hydrochloride has better stability than rosiglitazone maleate, and is very suitable for application in the manufacture of common pharmaceutical preparations. It is a thiazolidinedione antidiabetic drug, which can effectively control blood sugar by improving insulin sensitivity.
What are the applications of Application
rosiglitazone hydrochloride is an activator of PPARγ and an insulin sensitizer
Biological Activity
rosiglitazone is a blood glucose-lowering drugs, stimulating insulin secretion by binding to the ppar receptors in fat cells.
Properties of Rosiglitazone hydrochloride
| storage temp. | Store at -20°C |
| solubility | ≥39.4 mg/mL in DMSO; ≥2.81 mg/mL in H2O with gentle warming and ultrasonic; ≥51.2 mg/mL in EtOH with ultrasonic |
| form | solid |
| color | White to off-white |
| CAS DataBase Reference | 302543-62-0(CAS DataBase Reference) |
Safety information for Rosiglitazone hydrochloride
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Rosiglitazone hydrochloride
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