Ropivacaine hydrochloride
- CAS NO.：98717-15-8
- Empirical Formula: C17H27ClN2O
- Molecular Weight: 310.86
- MDL number: MFCD02102164
- EINECS: 1312995-182-4
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-11-19 15:53:33
What is Ropivacaine hydrochloride?
The Uses of Ropivacaine hydrochloride
anesthetic
The Uses of Ropivacaine hydrochloride
2-Piperidinecarboxamide hydrochloride is a useful research chemical compound.
Definition
ChEBI: The anhydrous form of (S)-ropivacaine hydrochloride.
Description
Ropivacaine hydrochloride is an aminoamide local anesthetic drug.
Mechanism of action
Local anesthetics like ropivacaine block the generation and conduction of nerve impulses, presumably by increasing the threshold for electrical excitation in the nerve, by slowing the propagation of the nerve impulse, and by reducing the rate of rise of the action potential. Specifically, they block the sodium channel and decrease chances of depolarization and consequent action potentials. In general, the progression of anesthesia is related to the diameter, myelination, and conduction velocity of affected nerve fibers.
Side Effects
Most side effects relate to administration technique (resulting in systemic exposure) or pharmacological effects of anesthesia, however allergic reactions can rarely occur.Systemic exposure to excessive quantities of ropivacaine mainly result in central nervous system (CNS) and cardiovascular effects.
Properties of Ropivacaine hydrochloride
| Melting point: | 260-262° |
| alpha | D25 -6.6° (c = 2 in water) |
| storage temp. | Store at -20°C |
| form | Solid |
| color | White to off-white |
| Water Solubility | ≥ 10.1mg/mL in Water |
| InChI | InChI=1S/C17H26N2O.ClH/c1-4-11-19-12-6-5-10-15(19)17(20)18-16-13(2)8-7-9-14(16)3;/h7-9,15H,4-6,10-12H2,1-3H3,(H,18,20);1H |
| CAS DataBase Reference | 98717-15-8(CAS DataBase Reference) |
Safety information for Ropivacaine hydrochloride
Computed Descriptors for Ropivacaine hydrochloride
| InChIKey | NDNSIBYYUOEUSV-UHFFFAOYSA-N |
| SMILES | N1(CCC)CCCCC1C(NC1=C(C)C=CC=C1C)=O.[H]Cl |
Ropivacaine hydrochloride manufacturer
Apothecon Pharmaceuticals Pvt Ltd
Vanquest Pharma Pvt Ltd
Triveni Interchem Private Limited
Narmada Organics
Ralington Pharma
Mac Chem Products (India) Pvt Ltd (Naprod Group)
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