(R)-(+)-TolBINAP

Synonym(s):(R)-Tol-BINAP

CAS NO.：99646-28-3
Empirical Formula: C48H40P2
Molecular Weight: 678.8
MDL number: MFCD00269856
EINECS: 1312995-182-4
SAFETY DATA SHEET (SDS)
Update Date: 2023-09-21 18:22:39

What is (R)-(+)-TolBINAP?

Chemical properties

White to cream powder

The Uses of (R)-(+)-TolBINAP

(R)-(+)-2,2'-Bis(di-p-tolylphosphino)-1,1'-binaphthyl is used as chiral catalyst ligand. (R)-T-BINAP complexes derived from rhodium precursors are used for the asymmetric hydroformylation of vinyl acetate. It is a catalysts used for reductive amination of ketones, Pt dications for cation trapping, Rh(I)-catalyst for hydrogenation of acetamidoacrylic acid derivatives.

The Uses of (R)-(+)-TolBINAP

(R)-T-BINAP complexes derived from rhodium precursors are used for the asymmetric hydroformylation of vinyl acetate. It may be employed as chiral catalyst for allylation of N-tosyl α-imino esters.

General Description

BINAP is based on a bis naphthalene backbone with different phosphine derivatives. 2,2′-bis(di-p-tolylphosphino)-1,1′-binaphthyl (p-Tol-BINAP)·AgF complex catalyzed asymmetric Mukaiyama-type aldol reaction is reported.

Properties of (R)-(+)-TolBINAP

Melting point:	255-257 °C
Boiling point:	754.4±60.0 °C(Predicted)
alpha	+156° (c 0.5, C6H6)
storage temp.	Inert atmosphere,Room Temperature
form	Powder
color	White to cream
optical activity	[α]20/D +162°, c = 0.5 in benzene
Water Solubility	Insoluble in water.
λmax	223nm(EtOH)(lit.)
CAS DataBase Reference	99646-28-3(CAS DataBase Reference)

Safety information for (R)-(+)-TolBINAP

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P304+P340:IF INHALED: Remove victim to fresh air and Keep at rest in a position comfortable for breathing. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P405:Store locked up.