(R)-5-Hydroxymethyldihydrofuran-2-one
Synonym(s):(R)-γ-Hydroxymethyl-γ-butyrolactone;(R)-4,5-Dihydro-5-hydroxymethyl-2(3H)-furanone;(R)-5-Hydroxymethyl-2-oxotetrahydrofuran
- CAS NO.:52813-63-5
- Empirical Formula: C5H8O3
- Molecular Weight: 116.12
- MDL number: MFCD00040528
- SAFETY DATA SHEET (SDS)
- Update Date: 2022-11-11 11:01:00
What is (R)-5-Hydroxymethyldihydrofuran-2-one?
The Uses of (R)-5-Hydroxymethyldihydrofuran-2-one
Versatile chiral synthon used in the synthesis of natural and unnatural products.
What are the applications of Application
(R)-(?)-Dihydro-5-(hydroxymethyl)-2(3H)-furanone is a versatile chiral synthon used in the synthesis of natural and unnatural products
Purification Methods
Purify it by column chromatography on Silica gel 60 (Merck 70-230 mesh) and eluting with 7% EtOH/73% CHCl3. IR
Properties of (R)-5-Hydroxymethyldihydrofuran-2-one
Boiling point: | 101-102 °C0.048 mm Hg(lit.) |
alpha | -56 º (c=3 in chloroform) |
Density | 1.238 g/mL at 20 °C(lit.) |
refractive index | n |
Flash point: | >230 °F |
storage temp. | 2-8°C |
pka | 14.12±0.10(Predicted) |
optical activity | [α]20/D 56°, c = 3 in chloroform |
BRN | 1680285 |
Safety information for (R)-5-Hydroxymethyldihydrofuran-2-one
Signal word | Warning |
Pictogram(s) |
Exclamation Mark Irritant GHS07 |
GHS Hazard Statements |
H302:Acute toxicity,oral |
Precautionary Statement Codes |
P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. |
Computed Descriptors for (R)-5-Hydroxymethyldihydrofuran-2-one
New Products
(R)-tert-butyl (4-methyl-1-oxopentan-3-yl)carbamate 2,2-diethoxyethanethioamide Tubulysin F Tubulysin G tetrahydro-4-methyl-2H-pyran 2,2-Difluoropropylamine hydrochloride 4,4-DIFLUOROPIPERIDINE 4-(Benzyloxy)-3-bromophenylacetic Acid 1-(1,1-Difluoroethyl)-2-fluorobenzene 2,2-Difluoropropanol 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate Imeglimin Hydrochloride IH Fuel shell Calcium Sodium Phosphosilicate IH 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol Latanoprostene Bunod Lubiprostone Magnesium Trisilicate Flame Retardant Zinc Borate methyl 3-fluoro-4- thiomorpholino phenylcarbamate (R)-(3-(3-fluoro-4- thiomorpholinophenyl)-2- oxooxazolidin-4-yl) methyl methanesulfonate 7-Methoxyquinoline-4-carbonitrile 7-Methoxyquinoline-4-carboxylic acidRelated products of tetrahydrofuran
Furazolidone
Trimethylolpropane
POLY(TETRAHYDROFURAN) STANDARD 20000
Tris(hydroxymethyl)aminomethane
2,5-Dihydrofuran
2,3-Dihydrobenzofuran
2,3-Dihydrofuran
2-Methylfuran
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