Medetomidine hydrochloride

CAS NO.：86347-15-1
Empirical Formula: C13H17ClN2
Molecular Weight: 236.74
EINECS: 645-306-0
SAFETY DATA SHEET (SDS)
Update Date: 2024-11-19 23:02:33

What is Medetomidine hydrochloride?

Description

Medetomidine hydrochloride is a potent, highly selective α2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for α2- and α1-adrenoceptors respectively). It is an imidazole compound. Medetomidine hydrochloride shows greater selectivity over α1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). In addition, it influences the adrenergic system by mimicking the action of adrenergic neurotransmitters.

Chemical properties

White Solid

The Uses of Medetomidine hydrochloride

α2-Adrenergic agonist. Sedative; analgesic.

The Uses of Medetomidine hydrochloride

Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor

The Uses of Medetomidine hydrochloride

An α2-Adrenergic agonist. Sedative; analgesic.

What are the applications of Application

Medetomidine hydrochloride is a potent and highly selective α2-adrenoceptor agonist used as an anesthetic and analgesic.

Definition

ChEBI: Medetomidine hydrochloride is a hydrochloride.

Biological Activity

medetomidine is a selective α2-adrenoceptor agonist, with ki of 1.08 nm, exhibts 1620-fold selectivity over α1-adrenoceptor.

Side Effects

Medetomidine hydrochloride is an alpha-2 adrenoreceptor agonist. Symptoms after absorption may involve clinical effects, including dose dependent sedation, respiratory depression, bradycardia, hypotension, a dry mouth, and hyperglycaemia. Ventricular arrhythmias have also been reported. Respiratory and haemodynamic symptoms should be treated symptomatically.

storage

Desiccate at RT

Properties of Medetomidine hydrochloride

Melting point:	164-166°C
storage temp.	Inert atmosphere,Store in freezer, under -20°C
solubility	Acetonitrile (Slightly), Methanol (Slightly), Water (Slightly)
form	Solid
color	White to Off-White
InChI	InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H

Safety information for Medetomidine hydrochloride

Signal word	Warning
Pictogram(s)	Exclamation Mark Irritant GHS07
GHS Hazard Statements	H317:Sensitisation, Skin H319:Serious eye damage/eye irritation
Precautionary Statement Codes	P280:Wear protective gloves/protective clothing/eye protection/face protection. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.