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HomeProduct name listMedetomidine hydrochloride

Medetomidine hydrochloride

Medetomidine hydrochloride Structural

What is Medetomidine hydrochloride?

Description

Medetomidine hydrochloride is a potent, highly selective α2-adrenoceptor agonist (Ki values are 1.08 and 1750 nM for α2- and α1-adrenoceptors respectively). It is an imidazole compound. Medetomidine hydrochloride shows greater selectivity over α1-adrenoceptors than clonidine and UK 14,304 (1620-, 220- and 300-fold respectively). In addition, it influences the adrenergic system by mimicking the action of adrenergic neurotransmitters.

Chemical properties

White Solid

The Uses of Medetomidine hydrochloride

α2-Adrenergic agonist. Sedative; analgesic.

The Uses of Medetomidine hydrochloride

Medetomidine is a selective α2-adrenoceptor agonist, with Ki of 1.08 nM, exhibts 1620-fold selectivity over α1-adrenoceptor

The Uses of Medetomidine hydrochloride

An α2-Adrenergic agonist. Sedative; analgesic.

What are the applications of Application

Medetomidine hydrochloride is a potent and highly selective α2-adrenoceptor agonist used as an anesthetic and analgesic.

Definition

ChEBI: Medetomidine hydrochloride is a hydrochloride.

Biological Activity

medetomidine is a selective α2-adrenoceptor agonist, with ki of 1.08 nm, exhibts 1620-fold selectivity over α1-adrenoceptor.

Side Effects

Medetomidine hydrochloride is an alpha-2 adrenoreceptor agonist. Symptoms after absorption may involve clinical effects, including dose dependent sedation, respiratory depression, bradycardia, hypotension, a dry mouth, and hyperglycaemia. Ventricular arrhythmias have also been reported. Respiratory and haemodynamic symptoms should be treated symptomatically.

storage

Desiccate at RT

Properties of Medetomidine hydrochloride

Melting point: 164-166°C
storage temp.  Inert atmosphere,Store in freezer, under -20°C
solubility  Acetonitrile (Slightly), Methanol (Slightly), Water (Slightly)
form  Solid
color  White to Off-White
InChI InChI=1S/C13H16N2.ClH/c1-9-5-4-6-12(10(9)2)11(3)13-7-14-8-15-13;/h4-8,11H,1-3H3,(H,14,15);1H

Safety information for Medetomidine hydrochloride

Signal word Warning
Pictogram(s)
ghs
Exclamation Mark
Irritant
GHS07
GHS Hazard Statements H317:Sensitisation, Skin
H319:Serious eye damage/eye irritation
Precautionary Statement Codes P280:Wear protective gloves/protective clothing/eye protection/face protection.
P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing.

Computed Descriptors for Medetomidine hydrochloride

InChIKey VPNGEIHDPSLNMU-UHFFFAOYSA-N
SMILES C(C1N=CNC=1)(C1C=CC=C(C)C=1C)C.Cl

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