pyridoxal
- CAS NO.:66-72-8
- Empirical Formula: C8H9NO3
- Molecular Weight: 167.16
- MDL number: MFCD00464806
- EINECS: 200-630-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-10-23 13:36:13
What is pyridoxal ?
Definition
ChEBI: A pyridinecarbaldehyde that is pyridine-5-carbaldehyde bearing methyl, hydroxy and hydroxymethyl substituents at positions 2, 3 and 4 respectively.
Enzyme inhibitor
This photosensitive aldehyde form of vitamin B6 (FW = 167.16 g/mol), systematically referred to as 3-hydroxy-5-(hydroxymethyl)-2-methyl-4- pyridinecarboxaldehyde, is the immediate precursor to the coenzyme pyridoxal 5’-phosphate (PLP) and is often a weaker competitive inhibitor of PLP binding to PLP-dependent enzymes). Pyridoxal is soluble in water (1 g/2 mL) and sensitive to heat, particularly at alkaline pH. The pKa values are 4.23 (phenol OH), 8.70 (pyridinium NH+), and 13.0. Pyridoxal has a lmax value of 252 nm at pH 7.0 (e = 8200 M–1cm–1). It is typically supplied as the hydrochloride. Target(s): O-acetylhomoserine aminocarboxypropyltransferase, or O-acetylhomoserine (thiol)-lyase; alanine racemase; aldehyde dehydrogenase; arginine decarboxylase; cystathionine b-lyase, or cystine lyase; cysteine synthase; dextransucrase; b-fructofuranosidase, or invertase; glutamate dehydrogenase; hemoglobin S polymerization; hydroxyacyl-glutathione hydrolase, or glyoxalase II; kynurenine 3- monooxygenase; lactoylglutathione lyase, or glyoxalase I; NMN nucleosidase; phosphopantothenoylcysteine decarboxylase; porphobilinogen synthase, or d-aminolevulinate dehydratase; pyridoxal kinase; pyridoxal phosphatase, weakly inhibited; starch phosphorylase; thiamin phosphatase; tyrosinase; and xanthine dehydrogenase.
Properties of pyridoxal
Melting point: | 165 °C |
Boiling point: | 412.8±40.0 °C(Predicted) |
Density | 1.360±0.06 g/cm3(Predicted) |
storage temp. | under inert gas (nitrogen or Argon) at 2-8°C |
pka | pKa 4.20 (H2O
t = 25
I = 0.1)(Approximate) |
form | Solid |
color | White to off-white |
EPA Substance Registry System | 4-Pyridinecarboxaldehyde, 3-hydroxy-5-(hydroxymethyl)-2-methyl- (66-72-8) |
Safety information for pyridoxal
Computed Descriptors for pyridoxal
New Products
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