1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
Synonym(s):3-Hydroxytriazolo[4,3-a]pyridine;s-Triazolo[4,3-a]pyridin-3-ol
- CAS NO.：6969-71-7
- Empirical Formula: C6H5N3O
- Molecular Weight: 135.12
- MDL number: MFCD00022632
- EINECS: 230-191-8
- SAFETY DATA SHEET (SDS)
- Update Date: 2025-01-27 09:38:02
![1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one Structural](https://img.chemicalbook.in/CAS/GIF/6969-71-7.gif)
What is 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one?
Chemical properties
Beige Solid
The Uses of 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one was used to prepare a congener of Trazodone (T718500) which was found to be a potent and selective inhibitor of synaptosomal uptake of 5-hydroxytryptamine.
Synthesis Reference(s)
Journal of Medicinal Chemistry, 28, p. 1394, 1985 DOI: 10.1021/jm00148a004
Properties of 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
| Melting point: | 231°C |
| Density | 1.51±0.1 g/cm3(Predicted) |
| storage temp. | 2-8°C |
| solubility | DMSO (Slightly), Methanol (Slightly, Heated, Sonicated) |
| form | Solid |
| pka | 7.86±0.20(Predicted) |
| color | Light Brown to Brown |
| BRN | 607433 |
| Stability: | Light Sensitive |
| CAS DataBase Reference | 6969-71-7(CAS DataBase Reference) |
Safety information for 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation H335:Specific target organ toxicity, single exposure;Respiratory tract irritation |
| Precautionary Statement Codes |
P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P271:Use only outdoors or in a well-ventilated area. P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. |
Computed Descriptors for 1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one
| InChIKey | LJRXNXBFJXXRNQ-UHFFFAOYSA-N |
1,2,4-Triazolo[4,3-a]pyridin-3(2H)-one manufacturer
GRK RESEARCH LABORATORIES PVT LTD
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Navone Specialties (OPC) Pvt Ltd
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Phone:+91-9323789882
Whatsapp: +91- 9323789882
product: 2H-[1,2,4] triazolo [4,3-A] pyridin-3-One 6969-71-7 99%
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