PYRAZOPHOS

CAS NO.：13457-18-6
Empirical Formula: C14H20N3O5PS
Molecular Weight: 373.36
MDL number: MFCD00055494
EINECS: 236-656-1
SAFETY DATA SHEET (SDS)
Update Date: 2025-10-23 17:25:30

What is PYRAZOPHOS?

The Uses of PYRAZOPHOS

Pyrazophos is a systemic fungicide that provides both protective and curative control of various fungal diseases such as powdery mildew (Podosphaera) on apples, stone fruits, bush fruits and strawberries, Erysiphe in cucurbits and tomatoes, Uncinula on vines and leaf blotch (Rhynchosporium) in cereals.

The Uses of PYRAZOPHOS

Fungicide.

The Uses of PYRAZOPHOS

Pyrazophos is an anticholinesterase pesticide used on fruits and vegetables and can be determined by gas chromatography/mass spectrometry and liquid chromatography with fluorescence detection.

Definition

ChEBI: A member of the class of pyrazolopyrimidines that is the ethyl ester of 2-[(diethoxyphosphorothioyl)oxy]-5-methylpyrazolo[1,5-a]pyrimidine-6-carboxylic acid. A fungicide used to control Erysiphe, Helminthosporium and ital>Rhynchospium in cereals.

Metabolic pathway

Limited information is available to describe the degradation and metabolic fate of pyrazophos. Hydrolytic cleavage of the P-O-pyrazolopyrimidine linkage is the primary metabolic pathway. Oxidative desulfuration of pyrazophos to pyrazophos-oxon is only a minor pathway, observed in the plant metabolism study (Scheme 1).

Metabolism

Its mode of action is believed to be the inhibition of melanin biosynthesis and the development of appressoria by fungal conidia. Formulation is available as emulsifiable concentrate (EC: 30%). Application rates on Oidium spp. are in the range of 15–30 g a.i./hl.

Degradation

Pyrazophos (1) is hydrolysed in acidic or alkaline solution (PM).

Properties of PYRAZOPHOS

Melting point:	51℃
Density	1.38±0.1 g/cm3(Predicted)
vapor pressure	2.2 x 10^-4 Pa (50 °C)
storage temp.	APPROX 4°C
pka	-1.37±0.40(Predicted)
form	neat
Water Solubility	4.2 mg l^-1 (25 °C)
Merck	13,8052
BRN	577209
EPA Substance Registry System	Pyrazophos (13457-18-6)

Safety information for PYRAZOPHOS

Signal word	Danger
Pictogram(s)	Skull and Crossbones Acute Toxicity GHS06 Environment GHS09
GHS Hazard Statements	H301:Acute toxicity,oral H332:Acute toxicity,inhalation H410:Hazardous to the aquatic environment, long-term hazard
Precautionary Statement Codes	P261:Avoid breathing dust/fume/gas/mist/vapours/spray. P264:Wash hands thoroughly after handling. P264:Wash skin thouroughly after handling. P270:Do not eat, drink or smoke when using this product. P273:Avoid release to the environment. P301+P310:IF SWALLOWED: Immediately call a POISON CENTER or doctor/physician.