Prunetin
Synonym(s):4′,5-Dihydroxy-7-methoxyisoflavone
- CAS NO.：552-59-0
- Empirical Formula: C16H12O5
- Molecular Weight: 284.26
- MDL number: MFCD00016951
- EINECS: 209-018-5
- SAFETY DATA SHEET (SDS)
- Update Date: 2024-07-02 08:54:56
What is Prunetin?
The Uses of Prunetin
Prunetin is isoflavone with diverse biological activities. Prunetin is an antagonist of the progesterone receptor when used at concentrations of 25 and 50 μM.
Definition
ChEBI: A hydroxyisoflavone that is genistein in which the hydroxy group at position 7 is replaced by a methoxy group.
Enzyme inhibitor
This Prunus species isoflavone (FW = 284.27 g/mol; CAS 552-59-0; melting point = 240°C), also known as 4’,5-dihydroxy-7- methoxyisoflavone and 5-hydroxy-3-(4-hydroxyphenyl)-7-methoxy-4H-1- benzopyran-4-one, inhibits alcohol dehydrogenase, aldehyde dehydrogenase, 3’,5’-cyclic-nucleotide phosphodiesterase, phosphodiesterase 4, and protein-tyrosine kinase. Its 4’-glucoside is prunitrin. Methylated isoflavones, such as prunetin, are rapidly converted by CYP1A2 to more active genistein and daidzein, which inhibit.formation of acetaminophen from phenacetin with an IC50 value of 16 μM.
Properties of Prunetin
| Melting point: | 240-242°C |
| Boiling point: | 346.76°C (rough estimate) |
| Density | 1.2160 (rough estimate) |
| refractive index | 1.6200 (estimate) |
| storage temp. | Inert atmosphere,Room Temperature |
| solubility | Soluble in Chloroform,Dichloromethane,Ethyl Acetate,DMSO,Acetone,etc. |
| form | Powder |
| pka | 6.35±0.20(Predicted) |
| color | White to off-white |
| BRN | 292155 |
| CAS DataBase Reference | 552-59-0(CAS DataBase Reference) |
Safety information for Prunetin
| Signal word | Warning |
| Pictogram(s) |
 Exclamation Mark Irritant GHS07 |
| GHS Hazard Statements |
H315:Skin corrosion/irritation H319:Serious eye damage/eye irritation |
| Precautionary Statement Codes |
P280:Wear protective gloves/protective clothing/eye protection/face protection. P302+P352:IF ON SKIN: wash with plenty of soap and water. P305+P351+P338:IF IN EYES: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continuerinsing. P332+P313:IF SKIN irritation occurs: Get medical advice/attention. P337+P313:IF eye irritation persists: Get medical advice/attention. |
Computed Descriptors for Prunetin
New Products
6-Bromo 2-Iodo Indole Pyridine 2,4,6-Tricarboxaldehyde Fosfomycin EP impurity D Rimegepant Impurity 3 Ivermectin EP Impurity B Tubulysin A Tubulysin M Tubulysin E Tubulysin F Diethyl Aluminium Cyanide (1.0 M in Toluene) (1R,2S)-2-(3,4-Difluorophenyl)cyclopropanamine Calcium Sodium Phosphosilicate IH Fuel shell 2-[[(3aR,4S,6R,6aS)-6-Aminotetrahydro-2,2-dimethyl-4H-cyclopenta-1,3-dioxol-4-yl]oxy]ethanol ethanedioate 2-[2-[3(S)-3[2-(7-chloro-2-quinolinyl) ethenyl] phenyl-3- hydroxyl propyl] phenyl]-2-propanol 2-(1-(Mercaptomethyl) cyclopropyl) acetonitrile (1-Isopropyl-1H-pyrazol-5-yl)boronic acid 5-Aminophthalazine Methyl 4-amino-3-(piperidin-1-yl)benzoate 4-(Azidomethyl)-3-chloropyridine (S)-Methyl 2-((tert-butoxycarbonyl)amino)-3-((S)-2-oxopyrrolidin-3-yl)propanoate 3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione 3-(4-bromo-1H-pyrazol-1-yl)-N,N-dimethylpropanamide 6-bromo-4-methyl-2-propyl-1H-1,3-benzodiazoleRelated products of tetrahydrofuran
You may like
-
Prunetin 98.00% CAS 552-59-0View Details
552-59-0 -
Prunetin CAS 552-59-0View Details
552-59-0 -
![3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dione](https://img.chemicalbook.in//ProductImageIndia/2024-09/Raw/54575d9a-6e8e-412f-ab6d-3557d5ed92e3.jpg)
3,6-Bis(4-iodophenyl)-2,5-dihydropyrrolo[3,4-c]pyrrole-1,4-dioneView Details
952145-70-9 -
Sidchem 730View Details -
Sidchem BT 20View Details -
1572177-89-9View Details
1572177-89-9 -
6390-09-6View Details
6390-09-6 -
6-Bromo indoleView Details