PROTAC K-Ras Degrader-1
- CAS NO.：2378258-52-5
- Empirical Formula: C53H62N10O10
- Molecular Weight: 999.14
- MDL number: MFCD32263411
- Update Date: 2024-07-02 08:55:01
What is PROTAC K-Ras Degrader-1?
Description
PROTAC K-Ras Degrader-1 (Compound 518) is potent K-Ras degrader based PROTAC, exhibits ≥70% degradation efficacy in SW1573 cells[1].
References
[1]. CREW, Andrew P., et al. MODULATORS OF PROTEOLYSIS AND ASSOCIATED METHODS OF USE. WO2019195609A2.
Properties of PROTAC K-Ras Degrader-1
| Density | 1.40±0.1 g/cm3(Predicted) |
| storage temp. | Store at -20°C |
| solubility | DMSO: 33.33 mg/mL (33.36 mM) |
| pka | 10.74±0.40(Predicted) |
| form | Solid |
| color | Light yellow to yellow |
Safety information for PROTAC K-Ras Degrader-1
Computed Descriptors for PROTAC K-Ras Degrader-1
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